Xue Ping, Huang Zong-Wen, Guo Jia, Zhao Jian-Lei, Li Yong-Hong, Wang Zhong-Chao
Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province 610041, China.
Zhong Xi Yi Jie He Xue Bao. 2005 Jul;3(4):263-5. doi: 10.3736/jcim20050404.
To study the therapeutic effects of Chaiqin Chengqi Decoction (CQCQD) in treating severe acute biliary pancreatitis.
Ninety patients with severe acute biliary pancreatitis were treated with CQCQD, and they were divided into two groups: early-treated group (54 patients treated with CQCQD within 3 days after the onset of severe acute biliary pancreatitis) and late-treated group (36 patients treated with CQCQD between 3 and 7 days after the onset of severe acute biliary pancreatitis). The complication incidence rate, operation rate, mortality rate and hospitalization period were examined.
The incidence rates of encephalopathy, infection and gastrointestinal hemorrhage were lower in the early-treated group than those in the late-treated group (P<0.05). The hospitalization periods of the early- and late-treated groups were (24.9+/-18.4) days and (51.6+/-45.9) days respectively (P<0.05). The general mortality rate was 14.4%. The mortality rate of the early-treated group (7.4%) was significantly lower as compared with that of the late-treated group (25.0%) (P<0.05). The operation rate of the early-treated group (11.1%) was also significantly lower as compared with that of the late-treated group (27.8%) (P<0.05).
Treating severe acute biliary pancreatitis with CQCQD in early stage may reduce the complication incidence rate, shorten the hospitalization period, and decrease the operation rate and mortality rate.
研究柴芩承气汤治疗重症急性胆源性胰腺炎的疗效。
90例重症急性胆源性胰腺炎患者采用柴芩承气汤治疗，分为早期治疗组（54例在重症急性胆源性胰腺炎发病后3天内采用柴芩承气汤治疗）和晚期治疗组（36例在重症急性胆源性胰腺炎发病后3至7天采用柴芩承气汤治疗）。观察并发症发生率、手术率、死亡率及住院时间。
早期治疗组脑病、感染及胃肠道出血的发生率低于晚期治疗组（P<0.05）。早期和晚期治疗组的住院时间分别为（24.9±18.4）天和（51.6±45.9）天（P<0.05）。总死亡率为14.4%。早期治疗组的死亡率（7.4%）显著低于晚期治疗组（25.0%）（P<0.05）。早期治疗组的手术率（11.1%）也显著低于晚期治疗组（27.8%）（P<0.05）。
早期用柴芩承气汤治疗重症急性胆源性胰腺炎可降低并发症发生率，缩短住院时间，降低手术率和死亡率。
