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全胃切除术和部分胃切除术后长期随访期间的营养摄入及营养状况的生化指标

Nutrient intake and biochemical markers of nutritional status during long-term follow-up after total and partial gastrectomy.

作者信息

Staël von Holstein C, Ibrahimbegovic E, Walther B, Akesson B

机构信息

Department of Surgery, University of Lund, Sweden.

出版信息

Eur J Clin Nutr. 1992 Apr;46(4):265-72.

PMID:1600923
Abstract

Dietary intake and biochemical nutritional status was studied in patients who had undergone total gastrectomy (TG, n = 10) or partial gastrectomy (PG, n = 10) several years ago. The dietary intake of energy, macronutrients and micronutrients was very similar in the two groups and was also similar to the intake reported for healthy subjects in Sweden. The concentration of alpha-tocopherol in serum was subnormal in the TG group and that of carotene in both groups of patients, and the values were also significantly lower in the TG group than in the PG group. This was probably due to fat malabsorption, since dietary intake was found to be adequate. The proportions of n-6 and n-3 polyunsaturated fatty acids in serum phosphatidylcholine were not significantly different between the TG and PG groups. Iron deficiency was found in three patients in the TG group. Three patients (two TG, one PG) had elevated serum alkaline phosphatase and one patient (PG) had subnormal cobalamin concentration. For ascorbic acid, folate, calcium, phosphorus, magnesium, zinc, copper and selenium, the serum concentrations were normal or close to normal. Although the stores of some micronutrients seemed smaller after total gastrectomy, no major differences in nutritional status were found between the TG and PG groups. For the demonstration of decreased micronutrient stores during long-term follow-up after gastrectomy, an extended profile of biochemical markers of nutritional status is recommended.

摘要

对几年前接受过全胃切除术(TG,n = 10)或部分胃切除术(PG,n = 10)的患者的饮食摄入和生化营养状况进行了研究。两组患者的能量、常量营养素和微量营养素的饮食摄入量非常相似,也与瑞典健康受试者报告的摄入量相似。TG组血清α-生育酚浓度低于正常水平,两组患者血清胡萝卜素浓度均低于正常水平,且TG组的值显著低于PG组。这可能是由于脂肪吸收不良,因为发现饮食摄入量是充足的。TG组和PG组血清磷脂酰胆碱中n-6和n-3多不饱和脂肪酸的比例无显著差异。TG组有3例患者缺铁。3例患者(2例TG,1例PG)血清碱性磷酸酶升高,1例患者(PG)钴胺素浓度低于正常水平。抗坏血酸、叶酸、钙、磷、镁、锌、铜和硒的血清浓度正常或接近正常。虽然全胃切除术后一些微量营养素的储备似乎较少,但TG组和PG组在营养状况方面未发现重大差异。为了在胃切除术后的长期随访中证明微量营养素储备减少,建议采用更广泛的营养状况生化标志物谱。

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