Occupational risk factors for brain cancer in Canada.

作者信息

Pan Sai Yi, Ugnat Anne-Marie, Mao Yang

机构信息

Surveillance and Risk Assessment Division, Centre for Chronic Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario, Canada.

出版信息

J Occup Environ Med. 2005 Jul;47(7):704-17. doi: 10.1097/01.jom.0000165747.95801.c5.

OBJECTIVE

We sought to examine the impact of occupational exposure on brain cancer risk.

METHODS

Mailed questionnaires were used to collect information on lifetime employment history, occupational exposure to 18 chemicals, and other risk factors for 1009 incident cases of brain cancer and 5039 control subjects in Canada in 1994 to 1997.

RESULTS

People exposed to asphalt and welding had respective odds ratio (and 95% confidence interval) of 1.29 (1.02-1.62) and 1.26 (0.98-1.45). An increased risk of brain cancer might be associated with exposure to asbestos, benzene, mineral or lubricating oil, isopropyl oil, and wood dust and with following occupations: teaching; protective service; metal processing and related jobs, and metal shaping and forming; knitting in textile processing; construction trades; and transport equipment operating.

CONCLUSIONS

Our study suggests a possible role for occupational exposure in the etiology of brain cancer.