Zhong Guo-yue, Huang Xiao-ping, Ma Kai-sen, Chen Shi-jiang, Qin Song-yun
Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China.
Zhongguo Zhong Yao Za Zhi. 2005 Apr;30(7):495-7.
To study the dynamic change of the ingredients of Coptis chinensis and evaluate the quality of the crude drugs from main producing areas.
The ingredients of samples from Shizhu and Wuxi counties in Chongqing, Hongya and Dayi counties in Sichuan, Zhenping county in Shanxi, Lichuan county in Hubei were analyzed for berberine, coptisine, jatrorrhizine, palmatine and the total alkaloids by HPLC and UV methods.
The contents of measured indexes were mostly highest in 5-years-old C. chinensis. Considering factors such as the yield, it is reasonable to harvest the 5-years-old C. chinensis. There are minor differences in condents of C. chinensis from different areas, all tested samples met the pharmacopoeial standards. It is concluded that the general quality of C. chinensis was good and acceptable.
研究黄连成分的动态变化，评价主产区药材质量。
采用高效液相色谱法（HPLC）和紫外分光光度法（UV），对重庆石柱县和巫溪县、四川洪雅县和大邑县、陕西镇坪县、湖北利川县所产黄连样品中的小檗碱、黄连碱、药根碱、巴马汀及总生物碱进行含量测定。
所测指标含量大多在5年生黄连中最高，综合产量等因素，5年生黄连采收较为合理。不同产地黄连含量存在一定差异，但所测样品均符合药典标准，表明黄连总体质量良好，可接受。
