Pan Hong-ping, Mo Xiang-lan, Yang Jia-zhen, Li Lu-li, Huang Zhen-lu, Ye Jin, Huang Jin
People's Hospital of Guangxi Autonomous Region, Nanning 530021, China.
Zhongguo Zhong Yao Za Zhi. 2005 Apr;30(7):538-40.
To study the effect of puerarin on the expression of Hsp (heat shock protein) 70 in the rats with cerebral injury induced by acute local ischemia.
Rat model of acute local cerebral ischemia was made by ligating middle cerebral artery. The Hsp70 expression in brain tissue was detected by SP method of immunohistochemistry.
The expression of Hsp70 was significantly higher in puerarintreated rats than those in the rats with cerebral ischemia.
Puerarin can enhance the level of Hsp70 expression in the rats with cerebral injury induced by acute local ischemia.
研究葛根素对急性局部缺血性脑损伤大鼠热休克蛋白（Hsp）70表达的影响。
通过结扎大脑中动脉制备大鼠急性局部脑缺血模型。采用免疫组织化学SP法检测脑组织中Hsp70的表达。
葛根素治疗组大鼠Hsp70的表达明显高于脑缺血大鼠。
葛根素可提高急性局部缺血性脑损伤大鼠Hsp70的表达水平。
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