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精索静脉曲张对大量前往不孕不育诊所就诊男性生育参数的影响。世界卫生组织。

The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. World Health Organization.

出版信息

Fertil Steril. 1992 Jun;57(6):1289-93.

PMID:1601152
Abstract

OBJECTIVE

To assess the role of varicocele in male infertility.

DESIGN

Data analysis of a large population of couples who were systematically investigated for infertility.

SETTINGS

Couples were recruited in 34 World Health Organization collaborating centers in 24 countries.

PATIENTS

Nine thousand thirty-four men presenting as partner of infertile couples.

INTERVENTIONS

None.

MAIN OUTCOME MEASURES

Physical findings, semen characteristics, coincidental pathology, and spontaneous pregnancies.

RESULTS

Varicocele was found in 25.4% of men with abnormal semen, compared with 11.7% of men with normal semen. It was accompanied by decreased testicular volume, impaired sperm quality, and decline of Leydig cell secretion. Spontaneous pregnancies were as frequent in couples in whom the men did or did not have varicocele.

CONCLUSION

Varicocele is clearly associated with impairment of testicular function and infertility.

摘要

目的

评估精索静脉曲张在男性不育中的作用。

设计

对大量因不育而接受系统调查的夫妇的数据进行分析。

地点

在24个国家的34个世界卫生组织合作中心招募夫妇。

患者

9034名作为不育夫妇一方的男性。

干预措施

无。

主要观察指标

体格检查结果、精液特征、合并病变及自然受孕情况。

结果

精液异常的男性中25.4%患有精索静脉曲张,而精液正常的男性中这一比例为11.7%。精索静脉曲张伴有睾丸体积减小、精子质量受损和睾丸间质细胞分泌功能下降。男性患有或未患有精索静脉曲张的夫妇自然受孕几率相同。

结论

精索静脉曲张显然与睾丸功能损害和不育有关。

相似文献

1
The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. World Health Organization.精索静脉曲张对大量前往不孕不育诊所就诊男性生育参数的影响。世界卫生组织。
Fertil Steril. 1992 Jun;57(6):1289-93.
2
The varicocele and male infertility.精索静脉曲张与男性不育症。
Urol Clin North Am. 1981 Feb;8(1):41-51.
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Nomograms for predicting changes in semen parameters in infertile men after varicocele repair.精索静脉曲张修复术后不育男性精液参数变化的预测列线图。
Fertil Steril. 2014 Jul;102(1):68-74. doi: 10.1016/j.fertnstert.2014.03.046. Epub 2014 May 10.
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Reproductive history and semen analysis in prevasectomy fertile men with and without varicocele.有或无精索静脉曲张的输精管切除术前可育男性的生殖史和精液分析
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Deterioration of semen parameters over time in men with untreated varicocele: evidence of progressive testicular damage.未治疗的精索静脉曲张男性精液参数随时间的恶化:渐进性睾丸损伤的证据。
Fertil Steril. 1992 Jan;57(1):174-7. doi: 10.1016/s0015-0282(16)54796-7.
6
Bilateral but not unilateral testicular hypotrophy predicts for severe impairment of semen quality in men with varicocele undergoing infertility evaluation.双侧而非单侧睾丸萎缩预示着接受不育评估的精索静脉曲张男性精液质量严重受损。
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7
Loss of fertility in men with varicocele.精索静脉曲张男性的生育能力丧失。
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Varicocele related testicular atrophy and its predictive effect upon fertility.精索静脉曲张相关的睾丸萎缩及其对生育能力的预测作用。
J Urol. 1994 Aug;152(2 Pt 2):788-90. doi: 10.1016/s0022-5347(17)32710-6.
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Relationship of varicocele to sperm output and fertility of male partners in infertile couples.精索静脉曲张与不育夫妇男性伴侣精子产量及生育力的关系。
J Urol. 1978 Dec;120(6):691-4. doi: 10.1016/s0022-5347(17)57332-2.
10
Varicocele repair for infertility: what is the evidence?精索静脉曲张修复治疗不育症:有何证据?
Curr Opin Urol. 2012 Nov;22(6):489-94. doi: 10.1097/MOU.0b013e328358e115.

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