Højberg Lise, Søndergård Eva, Pedersen Court
Department of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Scand J Infect Dis. 2005;37(6-7):522-4. doi: 10.1080/00365540510038514.
This report presents a case of infectious mononucleosis with severe neurological complications in a previously healthy young female. Both peripheral and cranial nerves were affected causing paralysis and need for assisted ventilation. There was a clear correlation between the symptoms and the serological findings, indicating that the causative agent was Epstein-Barr virus. The patient was treated with acyclovir, methylprednisolone and immunoglobulins. Two months later she had recovered completely. Epstein-Barr virus infection must be considered among the possible causes in patients with cranial nerve affection or Guillain-Barré syndrome.
本报告介绍了一例既往健康的年轻女性感染性单核细胞增多症伴严重神经并发症的病例。外周神经和颅神经均受影响，导致瘫痪并需要辅助通气。症状与血清学检查结果之间存在明显关联，表明病原体为EB病毒。患者接受了阿昔洛韦、甲泼尼龙和免疫球蛋白治疗。两个月后她已完全康复。对于患有颅神经病变或吉兰 - 巴雷综合征的患者，EB病毒感染必须被视为可能的病因之一。
