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大便失禁的患病率及负担:一项基于人群的女性研究

Prevalence and burden of fecal incontinence: a population-based study in women.

作者信息

Bharucha Adil E, Zinsmeister Alan R, Locke G Richard, Seide Barbara M, McKeon Kimberly, Schleck Cathy D, Melton L Joseph

机构信息

Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

出版信息

Gastroenterology. 2005 Jul;129(1):42-9. doi: 10.1053/j.gastro.2005.04.006.

Abstract

BACKGROUND & AIMS: The epidemiology of fecal incontinence (FI) is incompletely understood. We report the prevalence, clinical spectrum, health care-seeking behavior, and quality of life (QOL) in community women with FI.

METHODS

A questionnaire was mailed to an age-stratified random sample of 5300 Olmsted County, Minnesota, women identified by the Rochester Epidemiology Project. Symptom severity was assessed by a validated scale, and impact on QOL was evaluated for subjects who had any FI during the past year. The prevalence of FI was calculated with direct age adjustment to the 2000 US white female population.

RESULTS

Altogether, 2800 of 5300 women (53%) responded to the survey. The overall age-adjusted prevalence of FI in the past year was 12.1 per 100 (95% confidence interval, 11.0-13.1). The prevalence increased with age from 7 (third decade) to 22 (sixth decade) per 100 and was steady thereafter. Symptoms were mild (45%), moderate (50%), or severe (5%), and symptom severity was related to the impact of FI on QOL and physician-consulting behavior. Moderate to severe impact on >/=1 domain of QOL was reported by 6% with mild, 35% with moderate, and 82% with severe symptoms, whereas 5% with mild, 10% with moderate, and 48% with severe FI had consulted a physician for FI in the past year.

CONCLUSIONS

More than 1 of 10 adult women in the population have FI; almost 1 of 15 have moderate to severe FI. FI significantly impacts QOL and prompts health care utilization predominantly in women with moderate to severe symptoms.

摘要

背景与目的

粪失禁(FI)的流行病学情况尚未完全明晰。我们报告了社区中患有FI的女性的患病率、临床症状谱、就医行为及生活质量(QOL)。

方法

向明尼苏达州奥姆斯特德县5300名按年龄分层随机抽取的女性邮寄调查问卷,这些女性由罗切斯特流行病学项目识别。通过有效量表评估症状严重程度,并对过去一年中有任何FI症状的受试者的生活质量影响进行评估。采用直接年龄调整法将FI患病率调整至2000年美国白人女性人口水平。

结果

5300名女性中共有2800名(53%)回复了调查。过去一年中,经年龄调整后的FI总体患病率为每100人中有12.1例(95%置信区间为11.0 - 13.1)。患病率随年龄增长而升高,从每100人中有7例(第三个十年)升至22例(第六个十年),此后保持稳定。症状为轻度(45%)、中度(50%)或重度(5%),症状严重程度与FI对生活质量的影响及就医行为相关。报告显示,轻度症状者中有6%对生活质量的≥1个领域有中度至重度影响,中度症状者中有35%,重度症状者中有82%;而过去一年中,轻度FI者中有5%、中度FI者中有10%、重度FI者中有48%因FI咨询过医生。

结论

超过十分之一的成年女性患有FI;近十五分之一的女性患有中度至重度FI。FI对生活质量有显著影响,且主要促使有中度至重度症状的女性寻求医疗服务。

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