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[睾丸肿瘤。一家军队医院25年经验评估]

[Testicular neoplasms. Evaluation of the experience during 25 years in a military hospital].

作者信息

Diz Rodríguez R, Virseda Chamorro M, Paños Lozano P, Cabrera Cabrera J A, Arance Gil I, Alpuente Román C

机构信息

Servicio de Urología, Hospital Central de la Defensa, Madrid.

出版信息

Actas Urol Esp. 2005 May;29(5):457-64. doi: 10.1016/s0210-4806(05)73275-7.

DOI:10.1016/s0210-4806(05)73275-7
PMID:16013790
Abstract

OBJECTIVES

The testicular tumors are frequent in the young adult, coinciding with the incorporation to the Military Service. The objective of our work is to evaluate the tumoral characteristic, its evolution with the time and the result of the treatments used in our center for this type of tumors.

MATERIAL AND METHODS

We carried out a retrospective longitudinal study in a cohort of 98 patients with an average age of 28.6 years, subjected to orchiectomy for testicular tumor in our center between 1979 to 2004. In the study, we collected data referred to the age of the patients, the tumoral characteristic, the outcome of the treatment and the evolution of the tumor.

RESULTS

In 61% of the cases, the affected testicle was the right (significant differences). The most common histologyc type was the non seminomatous germ cell tumors (NSGCT) (65.3%). Followed by the pure seminomas (27.6%), and non germinal cell tumors (NGC) (7.1%). The NSGCT was diagnosed to a average age (23.2 years) significantly smaller that the other two types. The stage I was the most frequent (58%). The seminomas presented a stage I in a significantly bigger frequency (80%) that the others tumors. The data picked up during the 25 years didn't show a significant variation regarding the tumoral characteristic. The survival análisis indicated that the tumoral characteristic with better pronostic regarding the probability of tumoral recurrences were the seminomas and the tumoral stages I and II.

CONCLUSIONS

The non seminomatous germ cell tumors (NSGCT) are the most frequent testicular tumors in young adults. Most of the tumors are diagnosed in initial stages, and their pronostic is better in the case of the seminomas and in the stages I and II.

摘要

目的

睾丸肿瘤在年轻成年人中较为常见,这与他们开始服兵役的时间相吻合。我们这项工作的目的是评估这类肿瘤的特征、随时间的演变情况以及我们中心针对此类肿瘤所采用治疗方法的效果。

材料与方法

我们对98例平均年龄为28.6岁的患者进行了一项回顾性纵向研究,这些患者于1979年至2004年期间在我们中心接受了睾丸肿瘤睾丸切除术。在研究中,我们收集了有关患者年龄、肿瘤特征、治疗结果以及肿瘤演变情况的数据。

结果

在61%的病例中,患侧睾丸为右侧(存在显著差异)。最常见的组织学类型是非精原细胞性生殖细胞肿瘤(NSGCT)(65.3%)。其次是纯精原细胞瘤(27.6%)和非生殖细胞肿瘤(NGC)(7.1%)。NSGCT的诊断平均年龄(23.2岁)明显低于其他两种类型。I期最为常见(58%)。精原细胞瘤I期的出现频率(80%)明显高于其他肿瘤。在这25年期间收集的数据显示,肿瘤特征方面没有显著变化。生存分析表明,就肿瘤复发概率而言,预后较好的肿瘤特征是精原细胞瘤以及I期和II期肿瘤。

结论

非精原细胞性生殖细胞肿瘤(NSGCT)是年轻成年人中最常见的睾丸肿瘤。大多数肿瘤在早期被诊断出来,精原细胞瘤以及I期和II期肿瘤的预后较好。

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