Hui Andrew C F, Cheng Claudia, Lam Anita, Mok Vincent, Joynt Gavin M
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, SAR, China.
Eur Neurol. 2005;54(1):10-3. doi: 10.1159/000086755. Epub 2005 Jul 5.
Prediction of outcome after cardiac arrest has important ethical and socioeconomic implications. In general, delay in recovery of neurological function is associated with a worse prognosis. The presence of myoclonic seizures early after anoxia has been identified as a poor prognostic factor. We report a series of patients who developed postanoxic myoclonus status epilepticus (MSE), which was defined as continuous myoclonic seizure activity lasting 30 min or more. The results from 18 patients were retrieved, 11 men and 7 women, age ranging from 29 to 90 years. Myoclonus developed a mean of 11.7 h after cardiac arrest, persisting for a mean of 60.5 h. Sixteen (89%) died following MSE and the 2 survivors were highly dependent or remained in a persistent vegetative state, supporting the view that prognosis is poor in this condition.
心脏骤停后预后的预测具有重要的伦理和社会经济意义。一般来说，神经功能恢复延迟与预后较差相关。缺氧后早期出现肌阵挛性癫痫发作已被确定为不良预后因素。我们报告了一系列发生缺氧后肌阵挛性癫痫持续状态（MSE）的患者，其定义为持续肌阵挛性癫痫发作活动持续30分钟或更长时间。检索了18例患者的结果，其中男性11例，女性7例，年龄在29至90岁之间。肌阵挛在心脏骤停后平均11.7小时出现，平均持续60.5小时。16例（89%）患者在MSE后死亡，2名幸存者高度依赖他人或处于持续性植物状态，这支持了这种情况下预后较差的观点。
