Sugrue Michael
Trauma Department, Liverpool Hospital, Sydney, Australia.
Curr Opin Crit Care. 2005 Aug;11(4):333-8. doi: 10.1097/01.ccx.0000170505.53657.48.
This review will set forth the new consensus definitions for intra-abdominal pressure, intra-abdominal hypertension, and the abdominal compartment syndrome from the World Congress on the Abdominal Compartment Syndrome in December 2004. The review will explore the challenges in diagnosis, pathophysiology, and recent concepts in the treatment of abdominal compartment syndrome.
Intra-abdominal pressure greater than 12 mm Hg may exert adverse physiologic sequelae, progressing to intra-abdominal hypertension and full-blown abdominal compartment syndrome as intra-abdominal pressure increases. The first challenge is to recognize that abdominal compartment syndrome may be a potential problem in critically ill patients. Intra-abdominal pressure monitoring is essential for this. Continuous monitoring of intra-abdominal pressure and abdominal perfusion pressure adds real-time measurements and can be performed by way of the stomach or bladder. Intra-abdominal hypertension occurs in approximately 35% of patients in the intensive care unit, and abdominal compartment syndrome in approximately 5%.
Massive resuscitation is increasingly recognized as a major contributor to abdominal compartment syndrome. Prophylactic decompression and temporary abdominal closure have important roles in preventing tertiary or recurrent abdominal compartment syndrome. Failure to recognize and treat intra-abdominal hypertension will result in increased risk of renal impairment, visceral and intestinal ischemia, respiratory failure and death.
本综述将阐述2004年12月世界腹腔间隔室综合征大会提出的腹腔内压、腹腔内高压和腹腔间隔室综合征的新共识定义。该综述将探讨腹腔间隔室综合征在诊断、病理生理学及治疗方面的新观念所面临的挑战。
腹腔内压大于12 mmHg可能产生不良生理后果,随着腹腔内压升高,进而发展为腹腔内高压和典型的腹腔间隔室综合征。首要挑战是认识到腹腔间隔室综合征可能是重症患者的一个潜在问题。对此,腹腔内压监测至关重要。持续监测腹腔内压和腹腔灌注压可提供实时测量数据,且可通过胃或膀胱进行测量。在重症监护病房中,约35%的患者会发生腹腔内高压,约5%的患者会发生腹腔间隔室综合征。
大量液体复苏越来越被认为是腹腔间隔室综合征的主要促成因素。预防性减压和临时性腹壁关闭在预防三度或复发性腹腔间隔室综合征方面具有重要作用。未能识别和治疗腹腔内高压将导致肾功能损害、内脏和肠道缺血、呼吸衰竭及死亡的风险增加。