MMWR Morb Mortal Wkly Rep. 2005 Jul 15;54(27):676-8.
The Vaccine Safety Datalink (VSD) is a collaborative project involving CDC and eight health maintenance organizations (HMOs) in the United States. Computerized data on vaccination, medical outcomes, and patient demographics are collected and linked under a standard protocol at multiple HMOs. Beginning with the 2003-04 influenza season, the VSD team and one of the HMOs, Kaiser Permanente Northern California (KPNC), established an automated system for rapid detection of potentially adverse events after vaccinations among its members. During the 2004-05 influenza season, in response to the influenza vaccine shortfall and resulting prioritization of vaccine distribution, this rapid analysis system also was used to assess influenza vaccination coverage weekly among KPNC members. The results indicated that KPNC followed Advisory Committee on Immunization Practices (ACIP) prioritization guidelines by targeting influenza vaccination to children aged 6-23 months and adults aged >/=65 years. For the 2005-06 influenza season, the rapid analysis system should be expanded to include data from additional HMOs and more detailed information on vaccinees (e.g., high risk for influenza complications) to better characterize influenza vaccination coverage during the 2005-06 influenza season on a weekly basis.
疫苗安全数据链(VSD)是一个由美国疾病控制与预防中心(CDC)和八个健康维护组织(HMO)合作开展的项目。在多个健康维护组织中,按照标准方案收集并关联有关疫苗接种、医疗结果和患者人口统计学特征的计算机化数据。从2003 - 2004流感季开始,VSD团队与其中一个健康维护组织——北加利福尼亚凯撒医疗集团(KPNC)建立了一个自动化系统,用于快速检测其成员接种疫苗后可能出现的不良事件。在2004 - 2005流感季,鉴于流感疫苗短缺以及由此导致的疫苗分配优先级,该快速分析系统还被用于每周评估KPNC成员的流感疫苗接种覆盖率。结果表明,KPNC遵循了免疫实践咨询委员会(ACIP)的优先级指南,将流感疫苗接种目标人群定为6至23个月大的儿童以及65岁及以上的成年人。对于2005 - 2006流感季,应扩大快速分析系统,纳入更多健康维护组织的数据以及关于疫苗接种者的更详细信息(例如,流感并发症高风险人群),以便每周更好地描述2005 - 2006流感季的流感疫苗接种覆盖率情况。