MMWR Morb Mortal Wkly Rep. 2007 Sep 21;56(37):953-9.
Influenza epidemics occur seasonally and result in substantial morbidity and mortality among adults in the United States. Adult groups included in the 2007 Advisory Committee on Immunization Practices (ACIP) recommendation for annual influenza vaccination are persons aged 18-49 years with high-risk conditions (i.e., conditions associated with an increased risk for complications from influenza), persons aged > or =50 years, health-care personnel, and others who are household contacts or caregivers of persons at high risk (e.g., persons with high-risk conditions or children aged < or =59 months). In addition, adults who want to reduce the risk for becoming ill with influenza or of transmitting influenza to others should be vaccinated. Healthy People 2010 (HP2010) objectives include increasing vaccination levels to 90% for adults aged > or =65 years (objective 14-29a) and 60% for persons aged 18-64 years who have one or more high-risk conditions (objective 14-29c). From the 1992-93 through 2003-04 influenza seasons, seasonal influenza vaccination coverage estimates (based on Behavioral Risk Factor Surveillance System [BRFSS] data) among adults aged > or =65 years trended upward, except for three seasons (1997-98, 1999-00, and 2000-01) when no increases occurred (Figure). To evaluate recent state-specific progress toward the HP2010 objectives, CDC compared data from the 2004 and 2006 BRFSS surveys, which reflected vaccinations received during the 2003-04 and 2005-06 influenza seasons; data from the 2004-05 influenza season, which have been published previously, were not included in this comparison because that season was marked by a substantial shortage of influenza vaccine. This report describes the results of the analysis, which indicated that influenza vaccination coverage for the 2005-06 season did not return to levels observed before the vaccine shortage of 2004-05 and remained substantially below HP2010 targets. Comprehensive measures are needed to improve influenza vaccination coverage among adult populations in the United States, including increasing adoption of recommended adult immunization practices by health-care providers, raising public awareness about influenza vaccination, vaccinating throughout the influenza season, and ensuring stable supplies of readily available vaccine.
在美国,流感流行具有季节性,会导致大量成年人发病和死亡。2007年免疫实践咨询委员会(ACIP)建议每年进行流感疫苗接种的成年人群包括18至49岁的高危人群(即与流感并发症风险增加相关的疾病患者)、年龄大于或等于50岁的人群、医护人员以及其他与高危人群有家庭接触或为其提供护理的人员(如患有高危疾病的人或年龄小于或等于59个月的儿童)。此外,希望降低感染流感风险或向他人传播流感风险的成年人也应接种疫苗。《健康人民2010》(HP2010)目标包括将65岁及以上成年人的疫苗接种率提高到90%(目标14 - 29a),将有一个或多个高危疾病的18至64岁人群的疫苗接种率提高到60%(目标14 - 29c)。从1992 - 93年到2003 - 04年流感季节,65岁及以上成年人的季节性流感疫苗接种覆盖率估计值(基于行为危险因素监测系统[BRFSS]数据)呈上升趋势,但有三个季节(1997 - 98年、1999 - 00年和2000 - 01年)没有上升(图)。为评估近期各州在实现HP2010目标方面的进展,美国疾病控制与预防中心(CDC)比较了2004年和2006年BRFSS调查的数据,这两次调查反映了2003 - 04年和2005 - 06年流感季节的疫苗接种情况;之前已公布的2004 - 05年流感季节的数据未纳入此次比较,因为该季节存在流感疫苗严重短缺的情况。本报告描述了分析结果,结果表明2005 - 06年季节的流感疫苗接种覆盖率未恢复到2004 - 05年疫苗短缺之前的水平,仍远低于HP2010目标。需要采取综合措施来提高美国成年人群的流感疫苗接种覆盖率,包括医护人员更多地采用推荐的成人免疫接种做法、提高公众对流感疫苗接种的认识、在整个流感季节进行疫苗接种以及确保随时有稳定的可用疫苗供应。