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孕期使用选择性5-羟色胺再摄取抑制剂(SSRI)及其对胎儿和新生儿的影响:一项荟萃分析。

Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and effects on the fetus and newborn: a meta-analysis.

作者信息

Lattimore Keri A, Donn Steven M, Kaciroti Niko, Kemper Alex R, Neal Charles R, Vazquez Delia M

机构信息

Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Michigan, Ann Arbor, MI 48109-0254, USA.

出版信息

J Perinatol. 2005 Sep;25(9):595-604. doi: 10.1038/sj.jp.7211352.

Abstract

Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy and the postpartum period. These drugs are capable of crossing the placenta and being transferred to the newborn during lactation. This report reviews the available information regarding the effects of SSRIs on the fetus and newborn; including long-term neurodevelopmental outcomes.

摘要

选择性5-羟色胺再摄取抑制剂(SSRI)常用于治疗孕期及产后抑郁。这些药物能够穿过胎盘,并在哺乳期转移至新生儿体内。本报告回顾了关于SSRI对胎儿及新生儿影响的现有信息,包括长期神经发育结局。

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