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孕期使用选择性5-羟色胺再摄取抑制剂(SSRI)及其对胎儿和新生儿的影响:一项荟萃分析。

Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and effects on the fetus and newborn: a meta-analysis.

作者信息

Lattimore Keri A, Donn Steven M, Kaciroti Niko, Kemper Alex R, Neal Charles R, Vazquez Delia M

机构信息

Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Michigan, Ann Arbor, MI 48109-0254, USA.

出版信息

J Perinatol. 2005 Sep;25(9):595-604. doi: 10.1038/sj.jp.7211352.

DOI:10.1038/sj.jp.7211352
PMID:16015372
Abstract

Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy and the postpartum period. These drugs are capable of crossing the placenta and being transferred to the newborn during lactation. This report reviews the available information regarding the effects of SSRIs on the fetus and newborn; including long-term neurodevelopmental outcomes.

摘要

选择性5-羟色胺再摄取抑制剂(SSRI)常用于治疗孕期及产后抑郁。这些药物能够穿过胎盘,并在哺乳期转移至新生儿体内。本报告回顾了关于SSRI对胎儿及新生儿影响的现有信息,包括长期神经发育结局。

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Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and effects on the fetus and newborn: a meta-analysis.孕期使用选择性5-羟色胺再摄取抑制剂(SSRI)及其对胎儿和新生儿的影响:一项荟萃分析。
J Perinatol. 2005 Sep;25(9):595-604. doi: 10.1038/sj.jp.7211352.
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Prenatal SSRI exposure: Effects on later child development.产前暴露于选择性5-羟色胺再摄取抑制剂(SSRI):对儿童后期发育的影响。
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[Use of SSRIs during pregnancy and possible consequences for the development of the child].[孕期使用选择性5-羟色胺再摄取抑制剂及其对儿童发育可能产生的后果]
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Alterations in Resting-State Networks Following In Utero Selective Serotonin Reuptake Inhibitor Exposure in the Neonatal Brain.子宫内选择性 5-羟色胺再摄取抑制剂暴露后新生儿大脑静息态网络的改变。
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Sustained neurobehavioral effects of exposure to SSRI antidepressants during development: molecular to clinical evidence.发育期间暴露于选择性5-羟色胺再摄取抑制剂(SSRI)类抗抑郁药的持续神经行为影响:从分子到临床的证据
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Selective Serotonin Reuptake Inhibitors (SSRIs) in Pregnancy: An Updated Review on Risks to Mother, Fetus, and Child.选择性 5-羟色胺再摄取抑制剂(SSRIs)在妊娠中的应用:对母亲、胎儿和儿童风险的最新综述。
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[The Medical Products Agency about SSRI to pregnant women and adverse effects on the fetus. Long-term adverse effects are not proved, documentation is insufficient, more research is necessary].
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Treatment with selective serotonin reuptake inhibitors in the third trimester of pregnancy: effects on the infant.孕期晚期使用选择性5-羟色胺再摄取抑制剂的治疗:对婴儿的影响。
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