Pachinger O, Ogris E, Sochor H, Probst P, Zasmeta H, Kaliman J, Klicpera M
Acta Med Austriaca. 1979;6(2):35-42.
The function of the right ventricle (RV) and left ventricle (LV) was evaluated in 32 patients with congestive cardiomyopathies (COCM), 10 patients with hypertrophic cardiomyopathy (HOCM) and 21 normal subjects (N). In all these patients myocardial perfusion was analysed using quantitative 201 Tl myocardial perfusion imaging. In COCM parameters of RV and LV performance were significantly reduced (p less than 0.01); regional wall motion analysis revealed a reduced radial shortening ability. Regional Tl-distribution was not different in COCM and N; however, relative Tl-uptake was significantly reduced (p less than 0.05). 80% of all patients with COCM showed the RV free wall on Tl-perfusion scintigrams. These scintigraphic aspects allow a noninvasive differentiation of a disturbed LV function and the classification of coronary and primary myocardial etiology. In patients with COCM the scintigraphically determined thickness of septum and free wall of LV was increased as compared to N (p less than 0.05). The ratio septum/lateral wall of LV averaged 1.3 +/- 0.20. Quantitative analysis of regional Tl-uptake revealed increased segmental relative Tl-uptake. In the majority of patients there was a disproportionate septal hypertrophy on the gated blood pool scan in LAO. These radionuclide techniques allow a dynamic two-dimensional evaluation of the interventricular septum and the LV.
对32例充血性心肌病（COCM）患者、10例肥厚型心肌病（HOCM）患者和21名正常受试者（N）的右心室（RV）和左心室（LV）功能进行了评估。对所有这些患者均采用定量201铊心肌灌注显像分析心肌灌注情况。在COCM患者中，RV和LV的功能参数显著降低（p<0.01）；局部室壁运动分析显示径向缩短能力降低。COCM患者与正常受试者的局部铊分布无差异；然而，相对铊摄取显著降低（p<0.05）。80%的COCM患者在铊灌注闪烁图上显示RV游离壁。这些闪烁图表现有助于对LV功能紊乱进行无创鉴别，并对冠状动脉和原发性心肌病因进行分类。与正常受试者相比，COCM患者LV的室间隔和游离壁在闪烁图上测定的厚度增加（p<0.05）。LV的室间隔/侧壁比值平均为1.3±0.20。局部铊摄取的定量分析显示节段性相对铊摄取增加。在大多数患者中，在左前斜位门控血池扫描上存在不成比例的室间隔肥厚。这些放射性核素技术可对室间隔和LV进行动态二维评估。
