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充血性心肌病中心脏功能和心肌灌注的放射性核素评估。

Radionuclide assessment of cardiac performance and myocardial perfusion in congestive cardiomyopathies.

作者信息

Pachinger O, Ogris E, Sochor H, Probst P, Zasmeta H, Kaindl F

出版信息

Clin Cardiol. 1979 Aug;2(4):264-71. doi: 10.1002/clc.4960020405.

DOI:10.1002/clc.4960020405
PMID:262575
Abstract

To determine the reliability of radionuclide techniques in the diagnosis of congestive cardiomyopathy (COCM), the function of the right ventricle (RV) and left ventricle (LV) was evaluated in 32 patients with COCM and 21 normal subjects using radionuclide angiography (first pass and gated blood pool scan) combined with quantitative 201 thallium (Tl) myocardial perfusion imaging. In COCM parameters of RV and LV performance were significantly reduced (p less than 0.01); regional wall motion analysis revealed a reduced radial shortening ability (p less than 0.05). 201 Tl distribution within the myocardium was not different between COCM and N; however, segmental 201Tl-uptake was significantly reduced (p less than 0.01). RV free wall was visualized on 201Tl scan in 80% of patients with COCM. There was no correlation between RV free wall visualization and RV hemodynamics. Thus these scintigraphic aspects provide an atraumatic and sensitive technique for the evaluation of patients with COCM.

摘要

为了确定放射性核素技术在充血性心肌病(COCM)诊断中的可靠性,我们采用放射性核素血管造影(首次通过法和门控心血池扫描)结合定量201铊(Tl)心肌灌注显像,对32例COCM患者和21名正常受试者的右心室(RV)和左心室(LV)功能进行了评估。在COCM患者中,RV和LV功能参数显著降低(p<0.01);局部室壁运动分析显示径向缩短能力降低(p<0.05)。COCM患者与正常受试者心肌内201Tl分布无差异;然而,节段性201Tl摄取显著降低(p<0.01)。80%的COCM患者在201Tl扫描中可显示RV游离壁。RV游离壁显影与RV血流动力学之间无相关性。因此,这些闪烁显像方面为评估COCM患者提供了一种无创且敏感的技术。

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