Scherder E J A, Van Paasschen J, Deijen J-B, Van Der Knokke S, Orlebeke J F K, Burgers I, Devriese P-P, Swaab D F, Sergeant J A
Centre of Human Movement Sciences, Kÿksuniversiteit Groningen, Groningen, The Netherlands.
Aging Ment Health. 2005 May;9(3):272-80. doi: 10.1080/13607860500089930.
The primary goal of the present study was to examine whether in the elderly with mild cognitive impairment (MCI), the effect of physical activity measured directly following treatment, was reflected in an improvement in cognitive functioning in general or in executive functions (EF) in particular. Secondly, this study aimed to compare the effectiveness of two types of intervention, with varying intensities: walking and hand/face exercises. Forty-three frail, advanced elderly subjects (mean age: 86) with MCI were randomly divided into three groups, namely, a walking group (n=15), a group performing hand and face exercises (n=13), and a control group (n=15). All subjects received individual treatment for 30 minutes a day, three times a week, for a period of six weeks. A neuropsychological test battery, administered directly after cessation of treatment, assessed cognitive functioning. The results show that although a (nearly) significant improvement in tasks appealing to EF was observed in both the walking group and the hand/face group compared to the control group, the results should be interpreted with caution. Firm conclusions about the effectiveness of mild physical activity on EF in the oldest old can only be drawn after studies with larger number of subjects.
本研究的主要目的是检验在轻度认知障碍（MCI）的老年人中，治疗后直接测量的身体活动效果是否反映在一般认知功能的改善上，特别是执行功能（EF）的改善上。其次，本研究旨在比较两种不同强度干预措施的效果：步行和手部/面部锻炼。43名患有MCI的体弱高龄老年人（平均年龄：86岁）被随机分为三组，即步行组（n = 15）、进行手部和面部锻炼的组（n = 13）和对照组（n = 15）。所有受试者每天接受30分钟的个体化治疗，每周三次，为期六周。治疗结束后立即进行一组神经心理学测试，以评估认知功能。结果表明，尽管与对照组相比，步行组和手部/面部组在涉及执行功能的任务上都观察到了（几乎）显著改善，但对结果的解释应谨慎。只有在对更多受试者进行研究之后，才能就轻度身体活动对最年长者执行功能的有效性得出确凿结论。
