Department of Occupational Therapy, Graduate School, Yonsei University, Wonju, Republic of Korea.
Department of Occupational Therapy, College of Software and Digital Healthcare Convergence, Yonsei University, Wonju, Republic of Korea.
PLoS One. 2024 May 15;19(5):e0301035. doi: 10.1371/journal.pone.0301035. eCollection 2024.
The study aimed to investigate the survival rate of patients with dementia according to their level of physical activity and body mass index (BMI). A total of 5,789 patients with dementia were retrieved from the 2009-2015 National Health Insurance Sharing Service databases. Survival analysis was used to calculate the hazard ratio (HR) for physical activity and BMI. The study sample primarily comprised older adults (65-84 years old, 83.81%) and female (n = 3,865, 66.76%). Participants who engaged in physical activity had a lower mortality risk (HR = 0.91, p = 0.02). Compared to the underweight group, patients with dementia who had normal weight (HR = 0.86, p = 0.01), obesity (HR = 0.85, p = 0.03) and more than severe obesity (HR = 0.72, p = 0.02) demonstrated a lower mortality risk. This study emphasizes the significance of avoiding underweight and engaging in physical activity to reducing mortality risk in patients with dementia, highlighting the necessity for effective interventions.
本研究旨在探讨根据患者体力活动水平和体重指数（BMI）评估痴呆患者的生存率。共从 2009 年至 2015 年国家健康保险共享服务数据库中检索到 5789 例痴呆患者。生存分析用于计算体力活动和 BMI 的风险比（HR）。研究样本主要由老年人（65-84 岁，83.81%）和女性（n=3865，66.76%）组成。进行体力活动的参与者死亡率风险较低（HR=0.91，p=0.02）。与体重不足组相比，体重正常（HR=0.86，p=0.01）、肥胖（HR=0.85，p=0.03）和超肥胖（HR=0.72，p=0.02）的痴呆患者死亡率风险较低。本研究强调了避免体重不足和进行体力活动对降低痴呆患者死亡率风险的重要性，突出了采取有效干预措施的必要性。
