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[泪小管狭窄使泪点塞植入术复杂化。发生率及机制]

[Canalicular stenoses complicating the insertion of lacrimal plugs. Incidence and mechanisms].

作者信息

Fayet B, Benabderrazik S, Bernard J A, Deligne L, Hürbli T, D'Hermies F, Pouliquen Y

机构信息

Service d'ophtalmologie, Hôtel-Dieu, Paris.

出版信息

J Fr Ophtalmol. 1992;15(1):25-33.

PMID:1602102
Abstract

Changes in canalicular permeability following the insertion of punctum plugs was studied. This occlusive method was used to treat dry eye syndrome in 43 patients over a period of 32 months. All had normal canalicular patency, confirmed on the day of implantation. One hundred and five large plugs were used (2.4 plugs per patient). Twenty seven (25.7%) impassable acquired canalicular stenoses were seen in 15 patients. The canalicular site of the 27 stenoses was the same: junction between the vertical and horizontal portions. Among the 27 stenoses: 4 plugs had disappeared at an unknown time, with follow-up probing taking place after a mean interval of 7.5 (months range: 1 to 15 months); 17 plugs had been expelled after being in place for an average of 5 months (range: 1 to 12 months; standard deviation 3.47), with follow-up examination taking place on average 12 months after insertion (range: 6 to 17 months; standard deviation 3.4); and 6 plugs were still in place after a mean of 7 months (range: 2 to 15 months; standard deviation 4.73) and the stenosis was discovered when they were removed. They were intact. These 6 Cases eliminate any possibility of intra-canalicular migration of the prosthesis--of all or part--of the prosthesis. Stenoses appeared to develop rapidly: 45% of cases were discovered during the first 3 months. 16/27 (59%) of stenoses were investigated a second time, 6 months later on average (range: 2 to 12 months): these 16 canaliculi all remained impassable.

摘要

研究了插入泪点塞后泪小管通透性的变化。在32个月的时间里,采用这种阻塞方法治疗了43例干眼症患者。所有患者在植入当日泪小管通畅均正常。共使用了105个大塞子(每位患者2.4个)。在15例患者中发现了27处(25.7%)不可通过的后天性泪小管狭窄。这27处狭窄的泪小管部位相同:垂直部与水平部的交界处。在这27处狭窄中:4个塞子在未知时间消失,平均随访探查间隔为7.5个月(范围:1至15个月);17个塞子在平均放置5个月后(范围:1至12个月;标准差3.47)被排出,平均在插入后12个月进行随访检查(范围:6至17个月;标准差3.4);6个塞子在平均7个月后(范围:2至15个月;标准差4.73)仍在位,取出时发现狭窄。它们完好无损。这6例排除了假体全部或部分在泪小管内迁移的任何可能性。狭窄似乎发展迅速:45%的病例在最初3个月内被发现。27处狭窄中有16处(59%)在平均6个月后(范围:2至12个月)进行了第二次检查:这16条泪小管均仍不可通过。

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