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宫颈子宫内膜异位症:诊断与管理的困境

Cervical endometriosis: a diagnostic and management dilemma.

作者信息

Phadnis Saurabh V, Doshi Jagruti S, Ogunnaike Oluyemisi, Coady Andrew, Padwick Malcolm, Sanusi F A

机构信息

Department of Obstetrics and Gynaecology, West Hertfordshire Hospitals NHS Trust, Vicarage Road, Watford, WD18 0HB, United Kingdom.

出版信息

Arch Gynecol Obstet. 2005 Oct;272(4):289-93. doi: 10.1007/s00404-005-0006-1. Epub 2005 Oct 13.

DOI:10.1007/s00404-005-0006-1
PMID:16021490
Abstract

Cervical endometriosis is usually a retrospective finding on histology. We describe the diverse symptomatology of the disease, wherein a suspicion of diagnosis may be raised. A series of five patients with cervical endometriosis confirmed on histology was identified. One patient was asymptomatic but examination revealed a mass arising from the cervix. Two patients presented with persistent postcoital bleeding, one patient with intermenstrual bleeding and one patient with both intermenstrual and postcoital bleeding. All patients were followed up with colposcopy and cervical biopsy. Persistence of symptoms determined the mode of treatment which included surgical management in the form of large loop excision of the transformation zone (LLETZ) biopsy in four patients. Cervical endometriosis is a benign condition which may present with symptoms such as persistent post-coital bleeding or intermenstrual bleeding. Colposcopy and cervical biopsy are pivotal to the diagnosis. This condition can be managed expectantly in asymptomatic patients and persistent symptoms may warrant surgery.

摘要

宫颈子宫内膜异位症通常是组织学上的回顾性发现。我们描述了该疾病的多种症状表现,借此提高对其诊断的怀疑。我们确定了一组经组织学确诊的5例宫颈子宫内膜异位症患者。1例患者无症状,但检查发现宫颈有肿物。2例患者表现为性交后持续出血,1例患者表现为经间期出血,1例患者同时有经间期和性交后出血。所有患者均接受了阴道镜检查和宫颈活检。症状持续情况决定了治疗方式,其中4例患者接受了转化区大环形切除术(LLETZ)活检等手术治疗。宫颈子宫内膜异位症是一种良性疾病,可能表现为性交后持续出血或经间期出血等症状。阴道镜检查和宫颈活检对诊断至关重要。无症状患者可进行观察等待,而持续症状可能需要手术治疗。

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1
Cervical endometriosis: a diagnostic and management dilemma.宫颈子宫内膜异位症:诊断与管理的困境
Arch Gynecol Obstet. 2005 Oct;272(4):289-93. doi: 10.1007/s00404-005-0006-1. Epub 2005 Oct 13.
2
Post-coital bleeding: a rare and unusual presentation of cervical endometriosis.性交后出血:宫颈子宫内膜异位症的一种罕见且不寻常的表现。
Arch Gynecol Obstet. 2006 Mar;273(6):370-3. doi: 10.1007/s00404-005-0034-x. Epub 2006 Jan 22.
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Cervical endometriosis: case series and review of literature.宫颈子宫内膜异位症:病例系列及文献综述
J Obstet Gynaecol Res. 2010 Aug;36(4):916-9. doi: 10.1111/j.1447-0756.2010.01209.x.
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[Blue cyst of the uterine cervix--colposcopy and aspiration cytology diagnosis of endometriosis].[子宫颈蓝色囊肿——子宫内膜异位症的阴道镜及穿刺细胞学诊断]
Cesk Gynekol. 1988 Sep;53(8):583-6.
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Cervical endometriosis: clinical character and management experience in a 27-year span.宫颈子宫内膜异位症:27 年的临床特征和治疗经验。
Am J Obstet Gynecol. 2011 Nov;205(5):452.e1-5. doi: 10.1016/j.ajog.2011.06.070. Epub 2011 Jun 25.
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Superficial endometriosis of the uterine cervix: a report of 20 cases of a process that may be confused with endocervical glandular dysplasia or adenocarcinoma in situ.子宫颈浅表性子宫内膜异位症:20例报告,该病症可能与子宫颈腺上皮发育异常或原位腺癌相混淆。
Int J Gynecol Pathol. 1999 Jul;18(3):198-205.
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Successful management of a massive hemorrhage due to rupture of cystic cervical endometriosis by a loop electrosurgical excision procedure.采用环形电切术成功治疗宫颈子宫内膜异位囊肿破裂导致的大出血。
Fertil Steril. 2008 Apr;89(4):991.e13-5. doi: 10.1016/j.fertnstert.2007.04.011. Epub 2007 Jul 2.
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Polypoid endometriosis of the uterine cervix with Arias-Stella reaction in a patient taking phytoestrogens.服用植物雌激素患者的宫颈息肉样子宫内膜异位症伴 Arias-Stella 反应。
Int J Gynecol Pathol. 2010 Mar;29(2):185-8. doi: 10.1097/PGP.0b013e3181b7015e.
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Persistent post-coital bleeding due to cervical endometriosis.宫颈子宫内膜异位症导致的性交后持续出血。
J Obstet Gynaecol. 2004 Jun;24(4):468-9. doi: 10.1080/01443610410001696978.
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Colposcopy and electrocoagulation-diathermy for cervical dysplasia and carcinoma in situ.阴道镜检查及电凝透热疗法治疗宫颈发育异常和原位癌。
Obstet Gynecol. 1971 Apr;37(4):623-8.

引用本文的文献

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Transhymenal Vaginoscopic Resection of a Large Polypoid Cervical Endometriosis in an Adolescent Girl: Case Report and Literature Review.青春期女孩巨大息肉样宫颈子宫内膜异位症的经处女膜阴道镜切除术:病例报告及文献综述
Reprod Sci. 2025 Jul 17. doi: 10.1007/s43032-025-01934-3.
2
Massive Hemorrhage Due to Cervical Endometriotic Cyst Rupture: Two Case Reports and a Literature Review.因宫颈子宫内膜异位囊肿破裂导致大出血:两例病例报告及文献复习。
Am J Case Rep. 2021 Nov 24;22:e934120. doi: 10.12659/AJCR.934120.
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Magnetic Resonance Imaging of Uterine Cervix: A Pictorial Essay.
子宫颈的磁共振成像:图文综述
Indian J Radiol Imaging. 2021 Apr;31(2):454-467. doi: 10.1055/s-0041-1734377. Epub 2021 Aug 4.
4
Endometriosis mimicking glandular atypia in a cervical cytology.宫颈细胞学检查中酷似腺上皮异型性的子宫内膜异位症
J Cytol. 2017 Jan-Mar;34(1):61-63. doi: 10.4103/0970-9371.197624.
5
Postcoital bleeding due to cervical endometriosis.宫颈子宫内膜异位症导致的性交后出血。
BMJ Case Rep. 2013 Jan 31;2013:bcr2012008209. doi: 10.1136/bcr-2012-008209.