一名患有IgG2缺乏症的HIV-1抗体阳性男性发生具核梭杆菌菌血症并伴有多发性肝脓肿。
Fusobacterium nucleatum bacteraemia with multiple liver abscesses in an HIV-I antibody positive man with IgG2 deficiency.
作者信息
Scoular A, Corcoran G D, Malin A, Evans B A, Davies A, Miller R F
机构信息
Department of Genito-urinary Medicine, UCMSM, Middlesex Hospital, London, U.K.
出版信息
J Infect. 1992 May;24(3):321-5. doi: 10.1016/s0163-4453(05)80038-6.
PMID:1602152
Abstract
Liver abscess formation due to Fusobacterium nucleatum is rare. We describe an HIV-I antibody positive man, with normal surrogate markers of cell-mediated immunity, who presented with F. nucleatum bacteraemia and liver abscess formation. He was found to have IgG2 subclass deficiency. This case illustrates the clinical importance of altered B-cell function in patients who are at an early stage of HIV disease.
摘要
由具核梭杆菌引起的肝脓肿形成较为罕见。我们描述了一名HIV-I抗体阳性男性，其细胞介导免疫的替代标志物正常，该患者出现具核梭杆菌菌血症和肝脓肿形成。发现他存在IgG2亚类缺陷。该病例说明了在HIV疾病早期患者中B细胞功能改变的临床重要性。
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