Garcia-Carretero Rafael
Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain.
BMJ Case Rep. 2019 Jan 29;12(1):e228237. doi: 10.1136/bcr-2018-228237.
infections can have a wide clinical spectrum, ranging from mild infections to severe sepsis and abscess formation. This range depends partly on the patient's underlying conditions, such as immunosuppression or malignancy. Fusobacteria are commensal rods in the oropharyngeal cavity and digestive tract, but should mucosal barrier disruption occur, in the presence of the above-mentioned predisposing conditions, fusobacteria can spread and cause infections in the soft tissues, liver and so on. An elderly woman was admitted with an altered level of consciousness (lethargy). The ensuing workup revealed a posterior oral cavity tumour (squamous cell carcinoma), bacteraemia and liver abscesses. Due to the severe sepsis, the patient was referred to our intensive care unit, but she passed away despite antibiotic treatment.
感染的临床谱广泛,从轻度感染到严重脓毒症及脓肿形成不等。这种范围部分取决于患者的基础状况,如免疫抑制或恶性肿瘤。梭杆菌是口咽腔和消化道中的共生杆菌,但如果发生黏膜屏障破坏,在上述易感条件存在时,梭杆菌可扩散并导致软组织、肝脏等部位感染。一名老年女性因意识水平改变(嗜睡)入院。随后的检查发现口腔后部肿瘤(鳞状细胞癌)、菌血症和肝脓肿。由于严重脓毒症,该患者被转诊至我们的重症监护病房,但尽管接受了抗生素治疗,她仍去世了。