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一名口咽恶性肿瘤患者因[具体病因未给出]导致菌血症和多发性肝脓肿。

Bacteraemia and multiple liver abscesses due to in a patient with oropharyngeal malignancy.

作者信息

Garcia-Carretero Rafael

机构信息

Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain.

出版信息

BMJ Case Rep. 2019 Jan 29;12(1):e228237. doi: 10.1136/bcr-2018-228237.

Abstract

infections can have a wide clinical spectrum, ranging from mild infections to severe sepsis and abscess formation. This range depends partly on the patient's underlying conditions, such as immunosuppression or malignancy. Fusobacteria are commensal rods in the oropharyngeal cavity and digestive tract, but should mucosal barrier disruption occur, in the presence of the above-mentioned predisposing conditions, fusobacteria can spread and cause infections in the soft tissues, liver and so on. An elderly woman was admitted with an altered level of consciousness (lethargy). The ensuing workup revealed a posterior oral cavity tumour (squamous cell carcinoma), bacteraemia and liver abscesses. Due to the severe sepsis, the patient was referred to our intensive care unit, but she passed away despite antibiotic treatment.

摘要

感染的临床谱广泛,从轻度感染到严重脓毒症及脓肿形成不等。这种范围部分取决于患者的基础状况,如免疫抑制或恶性肿瘤。梭杆菌是口咽腔和消化道中的共生杆菌,但如果发生黏膜屏障破坏,在上述易感条件存在时,梭杆菌可扩散并导致软组织、肝脏等部位感染。一名老年女性因意识水平改变(嗜睡)入院。随后的检查发现口腔后部肿瘤(鳞状细胞癌)、菌血症和肝脓肿。由于严重脓毒症,该患者被转诊至我们的重症监护病房,但尽管接受了抗生素治疗,她仍去世了。

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本文引用的文献

1
Clinical Features and Outcomes of Species Infections in a Ten-Year Follow-up.十年随访中物种感染的临床特征与结局
J Crit Care Med (Targu Mures). 2017 Nov 8;3(4):141-147. doi: 10.1515/jccm-2017-0029. eCollection 2017 Oct.
3
Fusobacterium liver abscess.梭杆菌性肝脓肿
Case Rep Gastroenterol. 2013 Nov 12;7(3):482-6. doi: 10.1159/000356821. eCollection 2013.
8
Pyogenic liver abscess: recent trends in etiology and mortality.化脓性肝脓肿:病因及死亡率的近期趋势
Clin Infect Dis. 2004 Dec 1;39(11):1654-9. doi: 10.1086/425616. Epub 2004 Nov 9.

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