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[1例由具核梭杆菌引起的肝脓肿病例,患者患有复发性牙周疾病]

[A case of liver abscess caused by Fusobacterium nucleatum in a patient with recurrent periodontal diseases].

作者信息

Kim Yong Hwan, Yoon Hee Jung, Park Chan Woong, Kim Jung Ho, Lee Min Kyung, Kim Ki Bang, Na Dong Jib, Kim Ji Myung

机构信息

Department of Internal Medicine, Eulji University College of Medicine, Eulji University Hospital, Daejeon, Korea.

出版信息

Korean J Gastroenterol. 2011 Jan;57(1):42-6. doi: 10.4166/kjg.2011.57.1.42.

Abstract

Fusobacteria are anaerobic gram-negative, non-spore forming bacilli found in normal flora of the oral cavity, urogenital tract, and gastrointestinal tract. Fusobacterium nucleatum has been seldom reported as a cause of liver abscess, particularly in immunocompetent hosts. A 55-year-old man with frequent periodontal disease visited our hospital with intermittent fever and headache for 2 months. Abdominal CT scan revealed an 8.2 × 6 cm mass in the right hepatic lobe with central low density. Abscess culture revealed F. nucleatum as the causative organism. Percutaneous abscess drainage and intravenous administration of antibiotics for 4 weeks improved symptoms and decreased the abscess size. We report a rare case of liver abscess due to F. nucleatum in an immunocompetent man with periodontal disease.

摘要

梭杆菌是厌氧的革兰氏阴性、无芽孢形成杆菌,存在于口腔、泌尿生殖道和胃肠道的正常菌群中。具核梭杆菌作为肝脓肿的病因鲜有报道,尤其是在免疫功能正常的宿主中。一名55岁男性,患有频发牙周疾病,因间歇性发热和头痛2个月前来我院就诊。腹部CT扫描显示右肝叶有一个8.2×6 cm的肿块,中心密度较低。脓肿培养显示具核梭杆菌为病原体。经皮脓肿引流和静脉注射抗生素4周后症状改善,脓肿大小缩小。我们报告了一例在免疫功能正常的牙周病男性患者中由具核梭杆菌引起的罕见肝脓肿病例。

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