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社区中酒精使用情况及药物合并使用情况——75岁及以上老年人潜在风险来源?

Community prevalence of alcohol use and concomitant use of medication--a source of possible risk in the elderly aged 75 and older?

作者信息

Aira Marja, Hartikainen Sirpa, Sulkava Raimo

机构信息

Inner-Savo Health Centre, Finland.

出版信息

Int J Geriatr Psychiatry. 2005 Jul;20(7):680-5. doi: 10.1002/gps.1340.

Abstract

AIMS

To explore alcohol use and concomitant use of prescription and over the counter (OTC) medicines in people aged 75 years or over.

DESIGN

Community-based randomized survey of home-dwelling elderly persons, Setting: the City of Kuopio, Finland.

PARTICIPANTS

Population-based random sample of 700 persons aged 75 years or over, of whom 601 participated (86%). Only home-dwellers (n = 523) were included in this study.

MEASUREMENTS

Alcohol use based on responses to questions concerning quantity and frequency, and CAGE questions. Use of prescription and non-prescription medicines. Mean corpuscular volume.

RESULTS

Of the participants, 44% used alcohol. Most alcohol drinkers used medications on a regular basis (86.9%) or as needed (87.8%), among them medicines known to have some potential interactions with alcohol. Elevated mean corpuscular volume was more widespread among alcohol drinkers than non drinkers.

CONCLUSION

Theoretical risks posed by alcohol use are not minimal in the older elderly, though the quantity of alcohol use is not considerable. Physicians and nurses should pay attention to chronic diseases and medications when counselling aged people about alcohol consumption. The question of clinical importance of alcohol-medication interactions needs to be studied further.

摘要

目的

探讨75岁及以上人群的酒精使用情况以及处方药和非处方药的同时使用情况。

设计

对居家老年人进行基于社区的随机调查,地点:芬兰库奥皮奥市。

参与者

基于人群的700名75岁及以上的随机样本,其中601人参与(86%)。本研究仅纳入居家者(n = 523)。

测量

根据关于饮酒量和频率的问题以及CAGE问题来确定酒精使用情况。处方药和非处方药的使用情况。平均红细胞体积。

结果

参与者中,44%饮酒。大多数饮酒者经常(86.9%)或按需(87.8%)使用药物,其中包括已知与酒精有潜在相互作用的药物。平均红细胞体积升高在饮酒者中比不饮酒者中更为普遍。

结论

尽管饮酒量不大,但在高龄老年人中,饮酒带来的理论风险并非微不足道。医生和护士在为老年人提供饮酒咨询时应关注慢性病和药物使用情况。酒精与药物相互作用的临床重要性问题需要进一步研究。

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