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谵妄的临床亚型及其在日常临床实践中的相关性:一项系统综述

Clinical subtypes of delirium and their relevance for daily clinical practice: a systematic review.

作者信息

de Rooij S E, Schuurmans M J, van der Mast R C, Levi M

机构信息

Department of Internal Medicine, Geriatric section, Academic Medical Center, Amsterdam.

出版信息

Int J Geriatr Psychiatry. 2005 Jul;20(7):609-15. doi: 10.1002/gps.1343.

DOI:10.1002/gps.1343
PMID:16021665
Abstract

BACKGROUND

Delirium is a disorder that besides four essential features consists of different combinations of symptoms. We reviewed the clinical classification of clusters of symptoms in two or three delirium subtypes. The possible implications of this subtype classification may be several. The investigation and exploration of clinical subtypes of delirium may provide information concerning the etiology, the pathogenesis, and the prognosis of delirium, but also may have therapeutic consequences.

METHODS

We searched several database for English-language articles. Selected articles were cross-checked for other relevant publications.

DATA SYNTHESIS AND CONCLUSION

We conducted a systematic review and retrieved ten clinical studies. The studies described in this review show different results, partly due to methodological problems and possibly by lack of a standard classification for delirium subtypes. According to the present literature a useful and reproducible method to classify (patterns of) symptoms in delirium subtypes seems to be the general rating of and division in to psychomotor subtypes. The Memorial Delirium Assessment Scale (MDAS) and the Dublin Delirium Assessment Scale (DAS) appear to be reliable methods, together with the new version of the Delirium Rating Scale (DRS-R-98).

摘要

背景

谵妄是一种除了四个基本特征外还由不同症状组合构成的病症。我们回顾了两到三种谵妄亚型中症状群的临床分类。这种亚型分类可能有多种潜在影响。对谵妄临床亚型的研究和探索可能会提供有关谵妄病因、发病机制和预后的信息,也可能会产生治疗方面的影响。

方法

我们在多个数据库中搜索英文文章。对所选文章交叉核对其他相关出版物。

数据综合与结论

我们进行了一项系统综述并检索到十项临床研究。本综述中描述的研究显示出不同结果,部分原因是方法学问题,也可能是由于缺乏谵妄亚型的标准分类。根据目前的文献,一种对谵妄亚型症状(模式)进行分类的有用且可重复的方法似乎是对精神运动亚型进行总体评分和划分。纪念谵妄评估量表(MDAS)、都柏林谵妄评估量表(DAS)以及新版谵妄评定量表(DRS-R-98)似乎都是可靠的方法。

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