Taillefer Marie-Christine, Dupuis Gilles, Hardy Jean-François, LeMay Sylvie
Department of Psychology, Montreal Heart Institute, Quebec, Canada.
Qual Life Res. 2005 Apr;14(3):769-78. doi: 10.1007/s11136-004-1667-0.
Quality of life (QoL) in valvular surgery may differ according to the underlying pathology and surgical technique used.
82 adults undergoing their first elective surgery for valve repair (VP; n = 9) or valve replacement (VR) with a mechanical valve (MVR; n = 57) or bioprosthesis (BVR; n = 16) were assessed before surgery and three months afterwards.
delta scores (postoperative-preoperative) on QoL measures (Quality of Life Systemic Inventory (QLSI) and SF-36).
Paired t tests and ANCOVAs with age and preoperative QoL scores as covariates.
QoL improves after surgery according to most subscales. According to group comparisons, patients with an MVR improve more than those with a BVR on the mental health subscale. In physical roles, patients with an MVR improve while those with a BVR deteriorate. In emotional roles, patients with a VR improve while those with a VP deteriorate. However, they are similar on all other subscales. Women improve more than men on leisure, affectivity and social functioning while the opposite holds true for mental health.
QoL improves after surgery. However, significant differences between groups are small because of a lack of statistical power.
瓣膜手术中的生活质量（QoL）可能因潜在病理状况和所采用的手术技术而异。
对82名首次接受瓣膜修复（VP；n = 9）或瓣膜置换（VR）手术的成年人进行评估，其中瓣膜置换采用机械瓣膜（MVR；n = 57）或生物假体（BVR；n = 16）。在手术前及术后三个月对他们进行评估。
生活质量测量指标（生活质量系统量表（QLSI）和SF - 36）的差值分数（术后 - 术前）。
采用配对t检验以及以年龄和术前生活质量分数作为协变量的协方差分析。
根据大多数分量表，术后生活质量有所改善。根据组间比较，在心理健康分量表上，接受机械瓣膜置换的患者比接受生物假体瓣膜置换的患者改善更多。在身体角色方面，接受机械瓣膜置换的患者有所改善，而接受生物假体瓣膜置换的患者则恶化。在情感角色方面，接受瓣膜置换的患者有所改善，而接受瓣膜修复的患者则恶化。然而，在所有其他分量表上他们的情况相似。在休闲、情感和社会功能方面，女性比男性改善更多，而在心理健康方面则相反。
术后生活质量有所改善。然而，由于缺乏统计学效力，组间的显著差异较小。
