Rybakova M G
Biull Eksp Biol Med. 1979 Dec;88(12):736-9.
Functional morphology of different zones of submandibular glands of albino rats was studied quantitatively with due regard for the stages of neuroendocrine system involution. It is shown that function of salivary glands during ageing is not altered; cyclic fluctuations with estral cycle phases are maintained similarly to those in young animals. But the basal level of proteins and mucopolysaccharides is reduced, their mean levels being equal to the minimal level in young animals. On the other hand, activation of enzymes responsible for energy and transport processes takes place and their relationships change. The data obtained prove the relationship between salivary and endocrine glands and confirm the viewpoint that in early age involution disintegration occurs between different parameters of the functional activity of salivary glands rather than there take place changes in their function.
在充分考虑神经内分泌系统退化阶段的情况下,对白化大鼠下颌下腺不同区域的功能形态进行了定量研究。结果表明,衰老过程中唾液腺的功能并未改变;与幼年动物相似,唾液腺功能随发情周期各阶段仍维持周期性波动。但是蛋白质和黏多糖的基础水平降低,其平均水平相当于幼年动物的最低水平。另一方面,负责能量和转运过程的酶被激活,且它们之间的关系发生了变化。所获得的数据证明了唾液腺与内分泌腺之间的关系,并证实了这样一种观点,即在幼年时期的退化过程中,唾液腺功能活动的不同参数之间发生了解体,而非其功能发生了变化。