Identification of broad specificity P450CAM variants by primary screening against indole as substrate.
作者信息
Celik Ayhan, Speight Robert E, Turner Nicholas J
机构信息
School of Chemistry, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, UKEH9 3JJ.
出版信息
Chem Commun (Camb). 2005 Aug 7(29):3652-4. doi: 10.1039/b506156c. Epub 2005 Jul 5.
DOI:10.1039/b506156c
PMID:16027900
Abstract
High-throughput screening of cytochrome P450CAM libraries, for their ability to oxidise indole to indigo and indirubin, has resulted in the identification of variants with activity towards the structurally unrelated substrate diphenylmethane.
摘要
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