Mahoney Mary-Helen, Joseph Mariamma, Temple Claire L F
School of Medicine, University of Western Ontario, Class of 2006.
J Surg Oncol. 2005 Aug 1;91(2):120-5. doi: 10.1002/jso.20284.
Lentigo maligna (LM) presents a challenge for complete surgical excision because of its extensive subclinical spread and predilection for the face.
To report our experience using the staged perimeter technique as an alternative to Mohs micrographic surgery for treatment of LM.
The perimeter procedure was performed on 11 patients with LM between March 2003 and June 2004. Data on patient and lesion characteristics, number of stages required to obtain clear margins, and follow-up was obtained by chart review.
A mean of 1.9 stages were required to achieve clear margins. A mean of 7 tissue specimens were sent to pathology per patient for evaluation. After a mean follow-up of 4.7 months, all patients were free of recurrence.
The perimeter technique is a simple method of margin-controlled excision of LM. The main advantage is that all margins are examined with permanent sections. The main drawback is that multiple operative sessions are required to complete the procedure. This technique does not require specific Mohs training and is therefore applicable to non-Mohs surgeons.
恶性雀斑样痣（LM）因其广泛的亚临床扩散及对面部的偏好，给完整手术切除带来挑战。
报告我们使用分期周边技术作为Mohs显微外科手术替代方法治疗LM的经验。
2003年3月至2004年6月期间，对11例LM患者实施了周边手术。通过查阅病历获取患者和病变特征、获得切缘阴性所需的分期数以及随访数据。
平均需要1.9个分期来获得切缘阴性。每位患者平均送检7个组织标本至病理科进行评估。平均随访4.7个月后，所有患者均无复发。
周边技术是一种简单的LM切缘控制切除方法。主要优点是所有切缘均用永久切片检查。主要缺点是需要多次手术来完成该操作。该技术不需要特定的Mohs培训，因此适用于非Mohs外科医生。
