[大鼠肠道壁微生物区系的研究]

[Study of the parietal microflora in the rat intestine].

作者信息

Vorob'ev A A, Nesvizhskiĭ Iu V, Bogdanova E A, Korneev M L, Matiukhina O B

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 2005 May-Jun(3):61-5.

Abstract

The article deals with the adaptation of the existing method of the isolation of microorganisms from parietal mucin of the intestine of experimental animals (rats) with a view to ensure the methodological uniformity of investigations. The effectiveness of the method of sparing disintegration of parietal mucin taken from the mucous membrane of the gastrointestinal tract, specially developed for human biomaterial, and its adequacy for microbiological investigations of the digestive organs of rats have been confirmed. A certain similarity between the microbiocenosis of the parietal mucin in the intestine of humans and rats has been established.

摘要

本文论述了对从实验动物（大鼠）肠道壁粘蛋白中分离微生物的现有方法进行调整，以确保研究方法的一致性。专门为人类生物材料开发的、用于胃肠道黏膜壁粘蛋白温和分解的方法的有效性，及其对大鼠消化器官微生物学研究的适用性已得到证实。已确定人类和大鼠肠道壁粘蛋白微生物群落之间存在一定的相似性。