Breteler M M, van den Ouweland F A, Grobbee D E, Hofman A
Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.
Neuroepidemiology. 1992;11 Suppl 1:23-8. doi: 10.1159/000110957.
The Rotterdam Elderly Study is designed as a community-based prospective follow-up study. The study population consists of almost 12,000 individuals aged 55 years and over who are living in an urban area in Rotterdam, the Netherlands. The objective of the study is to investigate the prevalence, incidence and determinants of neurogeriatric disorders, cardiovascular diseases, locomotor diseases and ophthalmologic diseases. In this paper we give a general outline of the Rotterdam Elderly Study, and a detailed description of the case finding and diagnostic procedures for the study of dementia. The risk factors for dementia that are assessed in the study are summarized.
鹿特丹老年研究是一项基于社区的前瞻性随访研究。研究对象包括近12000名年龄在55岁及以上、居住在荷兰鹿特丹市区的个体。该研究的目的是调查神经老年疾病、心血管疾病、运动系统疾病和眼科疾病的患病率、发病率及决定因素。在本文中,我们给出了鹿特丹老年研究的总体概况,以及痴呆症研究的病例发现和诊断程序的详细描述。总结了该研究中评估的痴呆症危险因素。