Hoppenbrouwers T, Hodgman J E, Arakawa K, Durand M, Cabal L A
Department of Pediatrics, University of Southern California School of Medicine, Los Angeles.
Neuropediatrics. 1992 Apr;23(2):75-81. doi: 10.1055/s-2008-1071317.
Nine of nineteen infants in this study exhibited two or more central apnea greater than or equal to 20 seconds when they were older than one week and between 32-36 weeks postconceptional age (PCA). We focused on the sequelae of these apneas. Apnea was separated from other morbidity associated with immaturity by the selection of consistently healthy infants. Following discharge, polygraphic tracings were obtained at 40, 44 and 52 weeks PCA in these non-apneic and previously apneic infants. Sleep states, minute by minute values for heart and respiratory rate, skin temperature and transcutaneous O2 (PtcO2) and CO2 (PtcCO2), apnea and transient decreases in PtcO2 were determined. Polygraphic measurements did not differentiate preterm infants with late apnea in the nursery from non-apneic ones. However, the apneic group exhibited a transient decrease in awakenings at 44 weeks PCA.
在本研究的19名婴儿中，有9名在出生一周后、孕龄（PCA）32 - 36周时出现了两次或更多次持续时间大于或等于20秒的中枢性呼吸暂停。我们重点关注这些呼吸暂停的后遗症。通过选择一直健康的婴儿，将呼吸暂停与其他与不成熟相关的疾病区分开来。出院后，对这些无呼吸暂停和曾有呼吸暂停的婴儿在PCA 40周、44周和52周时进行了多导睡眠图记录。确定了睡眠状态、每分钟的心率和呼吸频率、皮肤温度以及经皮氧分压（PtcO2）和二氧化碳分压（PtcCO2），呼吸暂停以及PtcO2的短暂下降情况。多导睡眠图测量未能区分在新生儿重症监护室中有晚期呼吸暂停的早产儿和无呼吸暂停的早产儿。然而，呼吸暂停组在PCA 44周时觉醒出现了短暂下降。
