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[兔视觉皮层和海马神经元在奇球测试中的可塑性有限]

[Limited plasticity of the rabbit visual cortex and hippocampal neurons in the oddball test].

作者信息

Polianskiĭ V B, Evtikhin D V, Sokolov E N, Kriuchkova A V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2005 May-Jun;55(3):360-7.

PMID:16033237
Abstract

The activity of 41 visual cortex and 20 hippocampal neurons from field CA1 was registered in experiments using oddball-stimulation with different color stimuli varied in intensity. 34% cortical and 37% hippocampal neurons demonstrated plasticity reactions. The significant increase of latest phases of neuronal activity (200-500 and 200-1000 ms after stimulation for cortical neurons and 300-550 ms for hippocampal neurons) was shown in responses to rare deviant stimuli, which had a less intensity than frequently standards. The quantity of the earliest neuronal phase of activity (40-120 ms after stimulation) was stabilized in responses to deviants and standards during the experiment. We propose that such increase of the latest phases of neuronal activity (the limited plasticity) may reflect the mechanisms of orienting reaction.

摘要

在使用不同强度颜色刺激的奇偶数刺激实验中,记录了41个视觉皮层神经元和20个海马体CA1区神经元的活动。34%的皮层神经元和37%的海马体神经元表现出可塑性反应。对强度低于频繁出现的标准刺激的罕见偏差刺激的反应中,神经元活动的后期阶段(皮层神经元刺激后200 - 500毫秒和200 - 1000毫秒,海马体神经元刺激后300 - 550毫秒)显著增加。在实验过程中,对偏差刺激和标准刺激的反应中,神经元活动最早阶段(刺激后40 - 120毫秒)的数量保持稳定。我们认为,神经元活动后期阶段的这种增加(有限的可塑性)可能反映了定向反应的机制。

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