Polyanskii V B, Evtikhin D V, Sokolov E N, Kryuchkova A V
Department of Higher Nervous Activity and Psychophysiology, MV Lomonosov Moscow State University, Russia.
Neurosci Behav Physiol. 2006 Jun;36(5):441-8. doi: 10.1007/s11055-006-0037-5.
The activity of 41 visual cortex neurons and 20 hippocampal field CA1 neurons was studied in rabbits during application of the oddball stimulation paradigm using color stimuli of different intensities. Among these cells, about one third were plastic cells (34% of cortical cells and 37% of hippocampal cells). These neurons showed significant increases in late responses, at times 200-500 and 200-1000 msec for visual cortex neurons and 300-550 msec for hippocampal neurons, to rare deviant stimuli of lesser intensity as compared with responses to the frequent standard stimuli of greater intensity. The initial peak of the response (40-120 msec), the "difference discharge," remained stable in responses to deviant and standard stimuli throughout the experiment. It is suggested that the strengthening of the late components of neuron responses to rare deviant stimuli (limited plasticity) reflects inclusion of the mechanisms of the orientational reflex.
在兔子身上，使用不同强度的颜色刺激，采用oddball刺激范式，研究了41个视觉皮层神经元和20个海马体CA1区神经元的活动。在这些细胞中，约三分之一是可塑性细胞（皮层细胞的34%和海马体细胞的37%）。与对强度较大的频繁标准刺激的反应相比，这些神经元对强度较小的罕见偏差刺激的晚期反应显著增加，视觉皮层神经元的晚期反应时间有时为200 - 500毫秒和200 - 1000毫秒，海马体神经元为300 - 550毫秒。在整个实验中，反应的初始峰值（40 - 120毫秒），即“差异放电”，在对偏差刺激和标准刺激的反应中保持稳定。有人认为，神经元对罕见偏差刺激的晚期成分反应增强（有限可塑性）反映了定向反射机制的参与。
