Rizzo M, Nawrot M, Blake R, Damasio A
Department of Neurology, University of Iowa College of Medicine, Iowa City.
Neurology. 1992 Jun;42(6):1175-80. doi: 10.1212/wnl.42.6.1175.
We surveyed a broad range of visual functions in a man who complained of abnormal color experience and inability to recognize faces following bilateral damage in the visual cortex. A lesion in his right visual cortex caused complete left visual field loss. A lesion in his left visual cortex, located entirely below the calcarine fissure, affected the vision in his remaining hemifield, the right one. Psychophysical testing showed severely defective color vision and pattern processing, but relatively normal luminance contrast detection thresholds. The finding of normal spatial contrast sensitivity and static stereopsis did not resemble a parvocellular defect of the type described in the monkey. The abilities to detect global coherent motion among noise, structure from motion and dynamic stereopsis, and to pursue moving targets showed normal motion processing at several levels. Together with normal flicker perception, these results excluded magnocellular or MT-like defects. Altogether, the findings mimic area V4 dysfunction.
我们对一名男子的多种视觉功能进行了调查，该男子抱怨在视觉皮层遭受双侧损伤后出现颜色感知异常和无法识别面孔的情况。其右侧视觉皮层的损伤导致左侧视野完全丧失。其左侧视觉皮层的损伤完全位于距状裂下方，影响了其剩余半侧视野（右侧视野）的视力。心理物理学测试显示其色觉和图案处理严重受损，但亮度对比度检测阈值相对正常。正常的空间对比度敏感性和静态立体视觉的发现并不类似于猴子中所描述的那种小细胞缺陷。在噪声中检测全局连贯运动、从运动中提取结构和动态立体视觉以及追踪移动目标的能力表明在多个层面上运动处理正常。连同正常的闪烁感知，这些结果排除了大细胞或类似MT区的缺陷。总体而言，这些发现模拟了V4区功能障碍。
