Koh Seong-Beom, Kim Byung-Jo, Lee Jongyun, Suh Sang-il, Kim Tack-Koon, Kim Seung-Hyun
Department of Neurology, Korea University Medical Center, Seoul, Republic of Korea.
Eur Neurol. 2008;60(4):174-8. doi: 10.1159/000148244. Epub 2008 Jul 31.
The extrastriate cortex is a visual processing structure beyond the striate cortex. This region contains cells that differ in selectivity for different features of stimuli such as color, motion and stereopsis. We studied stereopsis and color vision in patients with right extrastriate cerebral lesions.
Patients with right extrastriate cerebral lesions determined by MRI were recruited among consecutive inpatients. Patients with cognitive impairment (Mini Mental Status Examination score <24) were excluded. An ophthalmologist performed cortical visual testing: visual acuity, stereopsis, color vision and strabismus within 1 week after the insult.
Cortical visual testing was performed in 12 patients. Among the patients studied, 11 demonstrated abnormalities: reduced stereoacuity (8/12), color vision abnormalities (7/12). Seven patients showed complex cortical visual abnormalities. However, only 2 patients complained of subjective clinical symptoms. The MRI lesions in patients with disturbance of stereopsis were located in the dorsal occipitoparietal area and the ventral occipitotemporal area. Color vision abnormalities corresponded to lesions in the ventral occipitotemporal area.
Patients with lesions in the right extrastriate cortex tend to have disturbance of stereopsis and color vision abnormalities, even in the absence of visual complaints.
纹外皮层是位于纹状皮层之外的视觉处理结构。该区域包含对诸如颜色、运动和立体视觉等不同刺激特征具有不同选择性的细胞。我们研究了右侧纹外脑区病变患者的立体视觉和色觉。
在连续住院患者中招募经磁共振成像（MRI）确诊为右侧纹外脑区病变的患者。排除有认知障碍（简易精神状态检查表评分<24）的患者。一名眼科医生在损伤后1周内进行皮层视觉测试：视力、立体视觉、色觉和斜视。
对12例患者进行了皮层视觉测试。在所研究的患者中，11例表现出异常：立体视敏度降低（8/12），色觉异常（7/12）。7例患者表现出复杂的皮层视觉异常。然而，只有2例患者主诉有主观临床症状。立体视觉障碍患者的MRI病变位于枕顶叶背侧区域和枕颞叶腹侧区域。色觉异常与枕颞叶腹侧区域的病变相对应。
右侧纹外皮层病变的患者即使没有视觉主诉也往往存在立体视觉障碍和色觉异常。
