Stins John F, Tollenaar Marieke S, Slaats-Willemse Dorine I E, Buitelaar Jan K, Swaab-Barneveld Hanna, Verhulst Frank C, Polderman Tinca C, Boomsma Dorret I
Department of Biological Psychology, Free university of Amsterdam, The Netherlands.
Child Neuropsychol. 2005 Jun;11(3):285-94. doi: 10.1080/09297040490916938.
The aim of this study was to further refine the cognitive phenotype of attention-deficit/hyperactivity disorder (ADHD), with respect to the ability to sustain attention and executive functioning. Participants were 34 boys with ADHD (combined type) and 28 normal controls. The groups were closely matched for age and IQ. All participants were 12 years of age. Both groups performed a computerized sustained attention task and a response interference task. Measures related to speed, accuracy, and time on task were collected. We found that children with ADHD performed slower, less accurately, more impulsively, and with less stability than controls. Both groups produced more errors with increasing time on task, reflecting reduced vigilance. Importantly, no interaction with time on task was found. The overall pattern of results suggests that measures related to accuracy are more informative than measures related to speed of responding in refining the cognitive phenotype of ADHD.
本研究的目的是就持续注意力和执行功能的能力,进一步细化注意力缺陷多动障碍(ADHD)的认知表型。研究参与者为34名患有ADHD(混合型)的男孩和28名正常对照组。两组在年龄和智商方面进行了密切匹配。所有参与者均为12岁。两组都执行了一项计算机化的持续注意力任务和一项反应干扰任务。收集了与速度、准确性和任务时长相关的测量数据。我们发现,与对照组相比,患有ADHD的儿童表现得更慢、准确性更低、更冲动且稳定性更差。随着任务时间的增加,两组产生的错误都更多,这反映出警觉性降低。重要的是,未发现与任务时间的交互作用。结果的总体模式表明,在细化ADHD的认知表型方面,与准确性相关的测量指标比与反应速度相关的测量指标更具信息价值。