Lamers L M, Stalmeier P F M, McDonnell J, Krabbe P F M, van Busschbach J J
Instituut Beleid en Management Gezondheidszorg, Erasmus MC, Postbus 1738, 3000 DR Rotterdam.
Ned Tijdschr Geneeskd. 2005 Jul 9;149(28):1574-8.
To value EQ-5D health states by a general Dutch public. EQ-5D is a standardised questionnaire that is used to calculate quality-adjusted life-years for cost-utility analysis.
Descriptive.
A sample of 309 Dutch adults from Rotterdam and surroundings was asked to value 17 EQ-5D health states using the time trade-off method. Regression analysis was applied to the valuations of these 17 health states. By means of the estimated regression coefficients, which together constitute the so-called Dutch tariff, valuations can be determined for all possible EQ-5D health states. These values reflect the relative desirability of health states on a scale where 1 refers to full health and 0 refers to death. Societal valuations are necessary in order to correct life-years for the quality of life.
Complete data were obtained from 298 persons. Theywere representative for the Dutch population as far as age, gender and subjective health were concerned, but had a somewhat higher educational level. The estimated Dutch EQ-5D tariff revealed that the respondents assigned the most weight to (preventing) pain and anxiety or depression, followed by mobility, self-care and the activities of daily living. The Dutch tariff differed from the UK ('Measurement and Valuation of Health') tariff, which is currently used in Dutch cost-utility analyses. Compared to UK respondents, Dutch respondents assigned more weight to anxiety and depression and less weight to the other dimensions. Conclusion. The valuation of health states by this representative Dutch study group differed from the valuation that is currently used in Dutch cost-utility analyses.
由荷兰普通公众对EQ-5D健康状态进行估值。EQ-5D是一份标准化问卷，用于成本效用分析中计算质量调整生命年。
描述性研究。
来自鹿特丹及其周边地区的309名荷兰成年人样本被要求使用时间权衡法对17种EQ-5D健康状态进行估值。对这17种健康状态的估值进行回归分析。通过估计的回归系数（这些系数共同构成所谓的荷兰关税），可以确定所有可能的EQ-5D健康状态的估值。这些值反映了健康状态在1代表完全健康、0代表死亡的量表上的相对合意性。为了对生命年进行生活质量校正，社会估值是必要的。
从298人那里获得了完整数据。就年龄、性别和主观健康而言，他们代表了荷兰人口，但教育水平略高。估计的荷兰EQ-5D关税显示，受访者对（预防）疼痛和焦虑或抑郁赋予了最大权重，其次是行动能力、自我护理和日常生活活动。荷兰关税与目前荷兰成本效用分析中使用的英国（《健康的测量与估值》）关税不同。与英国受访者相比，荷兰受访者对焦虑和抑郁赋予了更多权重，对其他维度赋予了更少权重。结论。这个具有代表性的荷兰研究组对健康状态的估值与目前荷兰成本效用分析中使用的估值不同。
