Li Ming, Sun Li-zhong, Chang Qian, Zhu Jun-ming
Department of Cardiac Surgery, Fuwai Hospital, CAMS and PUMC, Beijing 100037, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Jun;27(3):367-9.
To summarize operational effect with surgical treatment of aortic regurgitation caused by Behcet's disease and discuss relevant surgical techniques for treatment of these conditions.
Eight patients with aortic regurgitation secondary to Behcet's disease and received surgery between April 1997 and August 2003 were retrospetively analyzed. Among them, two patients had their aortic valves replaced in other hospital before admitted to our hospital where one undertook aortic valve replacement (AVR), and the other undertook aortic root replacement (ARR). In six patients who were initially treated in our hospital, the surgical procedures for aortic regurgitation included AVR in three patients and ARR operation in other three patients in whom Bentall-type operation was conducted in two patients and Cabrol-type operation in one.
One patient died during hospital stay. The follow-up periods ranged from 3 months to 36 months. In five patients with prosthetic valve detachment or suture detachment, redo homograft replacement was required in one patient and redo AVR in 3, one patient had redo AVR twice, and the remaining one patient had no surgery at present. Three patients primarily operated by ARR operation have no complications.
The rate of prosthetic valve detachment is high in patients with Behcet's disease. ARR should be a first-line therapy for operation promised these patients.
总结白塞病所致主动脉瓣关闭不全的手术治疗效果，并探讨相关手术技巧。
回顾性分析1997年4月至2003年8月间8例因白塞病继发主动脉瓣关闭不全并接受手术治疗的患者。其中，2例患者在我院就诊前曾在其他医院行主动脉瓣置换术，1例在我院再次行主动脉瓣置换术（AVR），另1例行主动脉根部置换术（ARR）。在我院首次接受治疗的6例患者中，主动脉瓣关闭不全的手术方式包括3例行AVR，另外3例行ARR手术，其中2例行Bentall术式，1例行Cabrol术式。
1例患者住院期间死亡。随访时间为3个月至36个月。5例出现人工瓣膜脱离或缝线脱离，其中1例需再次行同种异体瓣膜置换术，3例行再次AVR，1例患者行两次再次AVR，其余1例患者目前未接受手术。3例首次行ARR手术的患者无并发症发生。
白塞病患者人工瓣膜脱离发生率较高。ARR应作为这类患者手术治疗的一线方案。
