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[孟德尔遗传糖尿病的研究进展]

[Research development of Mendelian inherited diabetes].

作者信息

Yang Yan-li, Meng Yan, Fang Fu-de

机构信息

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 100005, China.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Jun;27(3):382-7.

Abstract

Diabetes mellitus is a chronic syndrome of abnormal metabolism, determined by interaction of multifactorial genetic and environmental factors. Some specific types of diabetes, such as MODY, Leprechaunism, lipoatrophic diabetes, and Rabson-Mendenhall syndrome, are monogenic forms of diabetes and are inherited as a Mendelian pattern. The article reviews the research development of these Mendelian inherited diabetes will be reviewed.

摘要

糖尿病是一种慢性代谢异常综合征,由多因素遗传和环境因素相互作用决定。某些特定类型的糖尿病,如青少年发病的成年型糖尿病(MODY)、妖精貌综合征、脂肪萎缩性糖尿病和拉布森 - 门登霍尔综合征,是单基因形式的糖尿病,按孟德尔模式遗传。本文将综述这些孟德尔遗传糖尿病的研究进展。

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