Mi Ya-ping, Cheung Yiu-fai
Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Grantham Hospital, 125, Wong Chuk Hang Road, Hong Kong, China.
Int J Cardiol. 2006 May 24;109(3):329-34. doi: 10.1016/j.ijcard.2005.06.036. Epub 2005 Jul 20.
Survival of patients with PAIVS has improved significantly with adoption of a selective management approach based on RV and coronary arterial anatomy. We sought to determine the right (RV) and left ventricular (LV) function of patients with pulmonary atresia and intact ventricular septum (PAIVS) long-term after biventricular repair.
The regional ventricular function of 22 patients (11 males) aged 12.8+/-5.6 years with PAIVS after biventricular repair was assessed by tissue Doppler echocardiography (TDE). The results were compared to those of 22 age-matched controls.
When compared with controls, patients had significantly reduced myocardial tissue velocities, systolic and diastolic strain rate, and peak systolic strain in the basal, mid-, and apical segments of the RV free wall, interventricular septum and LV lateral wall (all with p<0.01). Heterogeneity of systolic and diastolic strain rate was observed in the RV free wall and interventricular septum in patients but not in controls.
Impairment of RV and LV regional longitudinal myocardial function occurs in patients with PAIVS late after biventricular repair.
