Pouillart P, Sastre X, Ollivier L, Tomeno B
Service de médecine oncologique, Institut Curie, Paris.
Rev Prat. 1992 Apr 1;42(7):827-30, 835-7.
Ewing's tumour is an undifferentiated round-cell sarcoma of children and adolescents arising from the skeleton. The translocation (11; 22) (q24; q12) is specific and could serve as a diagnostic marker. It has also enabled this tumour to be classified in the group of primary neuro-ectodermal tumours. Concerning treatment, intensive chemotherapy alternating with local therapy has improved the prognosis of localized Ewing's sarcoma of the limbs and, to a lesser degree, of the axial skeleton.
尤因肉瘤是一种发生于儿童和青少年骨骼的未分化圆形细胞肉瘤。11号和22号染色体（11；22）（q24；q12）之间的易位具有特异性，可作为诊断标志物。这也使得该肿瘤可被归类于原发性神经外胚层肿瘤组。关于治疗，强化化疗与局部治疗交替进行已改善了肢体局限性尤因肉瘤的预后，对于轴骨尤因肉瘤的预后改善程度较小。
