Ohnuma Naomi, Yoshida Hideo, Matsunaga Tadashi, Kouchi Katsunori, Hishiki Tomoro, Yamada Shinichi, Satoh Yoshiharu, Terui Keita
Pediatric Surgical Department, Chiba University Graduate School of Medicine, Chiba, Japan.
Nihon Geka Gakkai Zasshi. 2005 Jul;106(7):413-7.
The prognosis for children with malignant solid tumors has improved dramatically in Japan. During the last two decades, various groups have conducted sequential studies of the treatment of children with neuroblastoma, Wilms' tumor, and hepatoblastoma. Most institutes participated in nonrandomized trials designed to evaluate the safety and efficacy of combination chemotherapy, surgery, and radiotherapy in each group study and treated children with these tumors The results are reviewed and areas for future investigation are identified.
在日本，患有恶性实体瘤儿童的预后已得到显著改善。在过去二十年中，多个研究团队对神经母细胞瘤、肾母细胞瘤和肝母细胞瘤患儿的治疗进行了系列研究。大多数机构参与了旨在评估联合化疗、手术和放疗的安全性和有效性的非随机试验，在每组研究中对患有这些肿瘤的儿童进行治疗，并对结果进行了综述，确定了未来的研究方向。
