Rees J, Murray C S
Dermatology, University of Edinburgh, Edinburgh, UK.
Clin Exp Dermatol. 2005 Sep;30(5):471-3. doi: 10.1111/j.1365-2230.2005.01852.x.
The study of itch remains a neglected field, with a number of barriers limiting satisfactory therapy in the majority of instances. We review recent advances, focusing on the identification of the neural pathways, distinct from pain, that signal itch; methods to measure itch as scratch in humans; and the identification of a role for H4 receptors in mediating itch (in the mouse).
瘙痒研究仍然是一个被忽视的领域，在大多数情况下，有许多障碍限制了令人满意的治疗方法。我们回顾了最近的进展，重点关注与疼痛不同的、传递瘙痒信号的神经通路的识别；在人类中将瘙痒测量为抓挠的方法；以及H4受体在介导瘙痒（在小鼠中）方面作用的识别。
