7-脱氧-7-[(顺式和反式-3-氨基环己烷)硫代]卡红菌素酮的合成及其抗肿瘤特性
Synthesis and antitumor properties of 7-deoxy-7-[(cis- and trans-3-aminocyclohexane)thio]carminomycinone.
作者信息
Essery J M, Doyle T W, Schreiber R H
出版信息
J Med Chem. 1979 Nov;22(11):1425-8. doi: 10.1021/jm00197a029.
PMID:160462
Abstract
The synthesis of analogues of carminomycin in which the daunosamine group has been replaced by (cis- and trans-3-aminocyclohexane)thio moieties is described. The new compounds were found to exhibit none of the antitumor or antibiotic activity associated with carminomycin.
摘要
描述了柔红霉素胺基团已被（顺式和反式-3-氨基环己烷）硫代部分取代的洋红霉素类似物的合成。发现这些新化合物没有表现出与洋红霉素相关的任何抗肿瘤或抗生素活性。
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Synthesis and antitumor properties of 7-deoxy-7-[(cis- and trans-3-aminocyclohexane)thio]carminomycinone.7-脱氧-7-[(顺式和反式-3-氨基环己烷)硫代]卡红菌素酮的合成及其抗肿瘤特性
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