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临床药师对急性冠状动脉综合征患者再入院的影响。

Impact of the clinical pharmacist on readmission in patients with acute coronary syndrome.

作者信息

O'Dell Kate M, Kucukarslan Suzan N

机构信息

Department of Pharmacy, David Grant Medical Center, Thomas J Long School of Pharmacy and Health Sciences, University of the Pacific, Travis Air Force Base, CA 94535-1809, USA.

出版信息

Ann Pharmacother. 2005 Sep;39(9):1423-7. doi: 10.1345/aph.1E640. Epub 2005 Jul 26.

Abstract

BACKGROUND

Previous studies have reported a positive impact of pharmacists on care of patients with chronic illnesses. The impact of the clinical pharmacist on hospital readmission in patients with acute coronary syndromes (ACS) has yet to be evaluated, as of this writing.

OBJECTIVE

To evaluate the impact of the clinical pharmacist as a direct patient-care team member on cardiac-related readmission in patients admitted to the general cardiology unit with ACS.

METHODS

A prospective, nonrandomized observational study compared patients who received standard practice care with patients admitted to a service with a clinical pharmacist to provide care at the bedside. Patients admitted to and discharged from the general cardiology unit for ACS were included. The primary endpoint of the study was cardiac-related readmission at 30 days following hospital discharge. Secondary endpoints included length of stay and medication utilization. Interventions provided by the clinical pharmacist in the study group were documented.

RESULTS

Cardiac readmission at 30 days was similar between the groups (p = 0.59). In the subset of patients with unstable angina, readmission in the study group was significantly lower than in the control group (1.3% vs 9.1%; p = 0.04). Patients in both groups were similarly managed using drug therapy and invasive coronary interventions. The medical staff's rate of acceptance of recommendations provided by the pharmacist was 94.4%. The most common interventions were medication education and identification of indicated therapy.

CONCLUSIONS

The addition of pharmacists did not decrease readmission in patients with ACS. The finding of significant reduction in readmission in the subset of patients with unstable angina should be considered "hypothesis generating" for future randomized studies to confirm the results.

摘要

背景

既往研究报道了药剂师对慢性病患者护理的积极影响。截至撰写本文时,临床药剂师对急性冠状动脉综合征(ACS)患者住院再入院的影响尚未得到评估。

目的

评估临床药剂师作为直接参与患者护理的团队成员对入住综合心脏病科的ACS患者心脏相关再入院的影响。

方法

一项前瞻性、非随机观察性研究比较了接受标准常规护理的患者与入住有临床药剂师在床边提供护理服务的患者。纳入了因ACS入住并出院于综合心脏病科的患者。该研究的主要终点是出院后30天的心脏相关再入院。次要终点包括住院时间和药物使用情况。记录了研究组中临床药剂师提供的干预措施。

结果

两组30天的心脏再入院情况相似(p = 0.59)。在不稳定型心绞痛患者亚组中,研究组的再入院率显著低于对照组(1.3%对9.1%;p = 0.04)。两组患者在药物治疗和侵入性冠状动脉干预方面的管理相似。医务人员对药剂师提供的建议的接受率为94.4%。最常见的干预措施是药物教育和确定适宜治疗方案。

结论

增加药剂师并没有降低ACS患者的再入院率。在不稳定型心绞痛患者亚组中再入院率显著降低这一发现应被视为未来随机研究以证实结果的“产生假设”。

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