Region Zealand Hospital Pharmacy, Næstved Hospital, Ringstedgade 65, 4700, Næstved, Denmark,
Int J Clin Pharm. 2013 Dec;35(6):1137-51. doi: 10.1007/s11096-013-9837-1. Epub 2013 Aug 25.
The majority of hospitalised patients have drug-related problems. Clinical pharmacist services including medication history, medication reconciliation and medication review may reduce the number of drug-related problems. Acute and emergency hospital services have changed considerably during the past decade in Denmark, and the new fast-paced workflows pose new challenges for the provision of clinical pharmacist service.
To describe and evaluate a method for a clinical pharmacist service that is relevant and fit the workflow of the medical care in the acute ward.
Acute wards at three Danish hospitals.
The clinical pharmacist intervention comprised medication history, medication reconciliation, medication review, medical record entries and entry of prescription templates into the electronic medication module. Drug-related problems were categorised using The PCNE Classification V6.2. Inter-rater agreement analysis was used to validate the tool. Acceptance rates were measured as the physicians' approval of prescription templates and according to outcome in the PCNE classification.
Acceptance rate of the clinical pharmacists' interventions through the described method and inter-rater agreement using the PCNE classification for drug-related problems.
During 17 months, 188 patients were included in this study (average age 72 years and 55 % women). The clinical pharmacists found drug-related problems in 85 % of the patients. In the 1,724 prescriptions, 538 drug-related problems were identified. The overall acceptance rate by the physicians for the proposed interventions was 76 % (95 % CI 74-78 %). There was a substantial inter-rater agreement when using the PCNE classification system.
The methods for a clinical pharmacist service in the acute ward in this study have been demonstrated to be relevant and timely. The method received a high acceptance rate, regardless of no need for oral communication, and a substantial inter-rater agreement when classifying the drug-related problems.
大多数住院患者都存在药物相关问题。临床药师服务,包括用药史、用药重整和用药审核,可能会减少药物相关问题的数量。在过去十年中,丹麦的急性和急诊医院服务发生了巨大变化,新的快节奏工作流程给临床药师服务的提供带来了新的挑战。
描述和评估一种临床药师服务方法,该方法与急性病房的医疗工作流程相关且适用。
丹麦三家医院的急性病房。
临床药师干预包括用药史、用药重整、用药审核、病历记录和将处方模板输入电子用药模块。使用 PCNE 分类 V6.2 对药物相关问题进行分类。使用组内相关系数分析验证工具。接受率通过医生对处方模板的认可和 PCNE 分类中的结果来衡量。
通过所描述的方法和使用 PCNE 分类的药物相关问题的组内相关系数,临床药师干预的接受率。
在 17 个月期间,188 名患者被纳入本研究(平均年龄 72 岁,55%为女性)。临床药师在 85%的患者中发现了药物相关问题。在 1724 张处方中,共发现 538 个药物相关问题。医生对提出的干预措施的总体接受率为 76%(95%CI 74-78%)。使用 PCNE 分类系统时,存在显著的组内相关系数。
本研究中急性病房临床药师服务的方法被证明是相关且及时的。该方法的接受率很高,尽管不需要口头沟通,且在对药物相关问题进行分类时,组内相关系数也很高。