Komotar Ricardo J, Mocco J, Jones Jess E, Zacharia Brad E, Tihan Tarik, Feldstein Neil A, Anderson Richard C E
Department of Neurosurgery, Columbia University, New York, New York, USA.
Neurosurg Focus. 2005 Jun 15;18(6A):E7.
Pilomyxoid astrocytoma (PMA) is a recently defined pediatric brain tumor; PMAs were previously classified within the pilocytic astrocytoma (PA) category. Nevertheless, PMA has different histological features and has been shown to behave more aggressively than PA. These findings indicate that PMA may be a unique entity that is distinct from PA, or it may be an unusual variant. To increase awareness of PMA within the neurosurgical community, the authors review the diagnostic criteria, prognostic implications, and current management of this recently described pediatric low-grade astrocytoma.
毛黏液样星形细胞瘤(PMA)是一种最近定义的儿童脑肿瘤;PMA之前被归类于毛细胞型星形细胞瘤(PA)类别。然而,PMA具有不同的组织学特征,并且已被证明比PA的行为更具侵袭性。这些发现表明,PMA可能是一种与PA不同的独特实体,或者它可能是一种不寻常的变体。为了提高神经外科界对PMA的认识,作者回顾了这种最近描述的儿童低级别星形细胞瘤的诊断标准、预后意义和当前的治疗方法。