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噻氯匹定治疗期间发生脑出血和血栓性血小板减少性紫癜:病例报告

Cerebral hemorrhage and thrombotic thrombocytopenic purpura during ticlopidine treatment: case report.

作者信息

Capra R, Marcianò N, Fieni F, Capucci M, Ferremi P, Orlandini A

机构信息

Institute of Neurology, University of Brescia, Italy.

出版信息

Acta Neurol Belg. 1992;92(2):83-7.

PMID:1604963
Abstract

We report the second case of thrombotic thrombocytopenic purpura occurring during ticlopidine therapy. A cerebral hemorrhage was the first sign of the thrombocytopenia. Even if thrombocytopenia is a rare occurrence with ticlopidine therapy, we stress that platelets must be repeatedly monitored.

摘要

我们报告了第二例在噻氯匹定治疗期间发生的血栓性血小板减少性紫癜病例。脑出血是血小板减少的首个迹象。即便噻氯匹定治疗导致血小板减少的情况罕见,但我们强调必须反复监测血小板。

相似文献

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Cerebral hemorrhage and thrombotic thrombocytopenic purpura during ticlopidine treatment: case report.噻氯匹定治疗期间发生脑出血和血栓性血小板减少性紫癜:病例报告
Acta Neurol Belg. 1992;92(2):83-7.
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Thrombotic thrombocytopenic purpura associated with clopidogrel.与氯吡格雷相关的血栓性血小板减少性紫癜
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Ticlopidine-induced thrombotic thrombocytopenic purpura.噻氯匹定诱导的血栓性血小板减少性紫癜。
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Ticlopidine-induced thrombotic thrombocytopenic purpura: two case reports treated with plasma exchange plus steroids.噻氯匹定诱导的血栓性血小板减少性紫癜:两例采用血浆置换加类固醇治疗的病例报告
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Thrombotic thrombocytopenic purpura caused by ticlopidine, successfully treated by plasmapheresis.噻氯匹定所致血栓性血小板减少性紫癜,经血浆置换成功治疗。
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[Drug-induced thrombotic thrombocytopenic purpura].[药物性血栓性血小板减少性紫癜]
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Corticosteroids in the treatment of thrombotic thrombocytopenic purpura (TTP).皮质类固醇在血栓性血小板减少性紫癜(TTP)治疗中的应用
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Is ticlopidine really responsible for thrombotic thrombocytopenic purpura (TTP)?噻氯匹定真的是血栓性血小板减少性紫癜(TTP)的病因吗?
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[Thrombotic thrombocytopenic purpura with myocardial ischaemia: two case reports].[伴有心肌缺血的血栓性血小板减少性紫癜:两例病例报告]
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Thrombotic thrombocytopenic purpura associated with ticlopidine. A review of 60 cases.与噻氯匹定相关的血栓性血小板减少性紫癜。60例病例回顾。
Ann Intern Med. 1998 Apr 1;128(7):541-4. doi: 10.7326/0003-4819-128-7-199804010-00004.

引用本文的文献

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Hematologic dyscrasia associated with ticlopidine therapy: evidence for causality.噻氯匹定治疗相关的血液系统异常:因果关系的证据。
CMAJ. 2000 Nov 28;163(11):1441-8.
2
[Ticlopidine-associated thrombotic thrombocytopenic purpura (Morbus Moschcowitz)].
Med Klin (Munich). 2000 Jan 15;95(1):44-8. doi: 10.1007/BF03044980.
3
Adverse haematological effects of ticlopidine. Prevention, recognition and management.噻氯匹定的血液学不良反应。预防、识别与处理
Drug Saf. 1998 Aug;19(2):89-98. doi: 10.2165/00002018-199819020-00002.
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Ticlopidine. A review of its pharmacology, clinical efficacy and tolerability in the prevention of cerebral ischaemia and stroke.噻氯匹定。关于其在预防脑缺血和中风方面的药理学、临床疗效及耐受性的综述。
Drugs Aging. 1996 Mar;8(3):214-32. doi: 10.2165/00002512-199608030-00006.
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Platelet aggregation inhibitors in neurology.
Pharm World Sci. 1993 Dec 17;15(6):243-51. doi: 10.1007/BF01871125.