Nomura Y, Okuno T, Hara M, Young Y H
Department of Otolaryngology, University of Tokyo, Japan.
Acta Otolaryngol. 1992;112(2):186-91. doi: 10.1080/00016489.1992.11665401.
Collapse of the membranous labyrinth of the pars superior is a morphological change observed in 50% of animals with experimentally produced perilymph fistula, although the extent and degree of the collapse may vary greatly. The moderately collapsed membranous labyrinth may drift with CSF and/or perilymph pressure changes and this may stimulate sensory cells of the utricle and/or semicircular canals if the sensory cells are intact and the collapsed wall is in contact with the otolithic membrane and/or cupula. This condition is termed "floating" labyrinth. Caloric irregularity is often observed in electronystagmograms recorded from animals with experimental perilymph fistula. This is also observed in patients with perilymph fistula. Partial destruction of the vestibular organs using argon laser was performed in a patient with perilymph fistula who was incapacitated because of persistent positional vertigo after closure of the oval window fistula. Irradiation of the argon laser beam was directed to the macula utriculi, utriculoampullary nerve and singular nerve. The hearing of the patient was maintained, and vertigo disappeared after laser labyrinthectomy.
上半规管膜迷路塌陷是在50%实验性产生外淋巴瘘的动物中观察到的一种形态学改变，尽管塌陷的程度和范围可能有很大差异。中度塌陷的膜迷路可能会随着脑脊液和/或外淋巴压力变化而移动，如果感觉细胞完好且塌陷的壁与耳石膜和/或壶腹嵴接触，这可能会刺激椭圆囊和/或半规管的感觉细胞。这种情况被称为“漂浮”迷路。在实验性外淋巴瘘动物记录的眼震电图中经常观察到冷热试验异常。在因椭圆窗瘘封闭后持续位置性眩晕而丧失能力的外淋巴瘘患者中也观察到这种情况。对一名外淋巴瘘患者进行了氩激光前庭器官部分毁损术，该患者因椭圆窗瘘封闭后持续位置性眩晕而丧失能力。氩激光束照射椭圆囊斑、椭圆囊壶腹神经和单神经。患者听力得以保留，激光迷路切除术后眩晕消失。
